Justine C Rutter
Overview
Explore the profile of Justine C Rutter including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
14
Citations
175
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0
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Recent Articles
11.
Lin K, Rutter J, Xie A, Killarney S, Vaganay C, Benaksas C, et al.
Nat Cancer
. 2022 Jun;
3(7):837-851.
PMID: 35668193
Selinexor is a first-in-class inhibitor of the nuclear exportin XPO1 that was recently approved by the US Food and Drug Administration for the treatment of multiple myeloma and diffuse large...
12.
Su A, Ling F, Vaganay C, Sodaro G, Benaksas C, Bello R, et al.
Cancer Discov
. 2020 Aug;
10(12):1894-1911.
PMID: 32826232
Deciphering the impact of metabolic intervention on response to anticancer therapy may elucidate a path toward improved clinical responses. Here, we identify amino acid-related pathways connected to the folate cycle...
13.
Lin K, Rutter J, Xie A, Pardieu B, Winn E, Bello R, et al.
Nat Genet
. 2020 Mar;
52(4):408-417.
PMID: 32203462
Local adaptation directs populations towards environment-specific fitness maxima through acquisition of positively selected traits. However, rapid environmental changes can identify hidden fitness trade-offs that turn adaptation into maladaptation, resulting in...
14.
Lin K, Xie A, Rutter J, Ahn Y, Lloyd-Cowden J, Nichols A, et al.
Cell Metab
. 2019 Feb;
29(5):1217-1231.e7.
PMID: 30773463
Crosstalk between metabolic and survival pathways is critical for cellular homeostasis, but the connectivity between these processes remains poorly defined. We used loss-of-function CRISPR/Cas9 knockout screening to identify metabolic genes...