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Justin H Schripsema

Explore the profile of Justin H Schripsema including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 420
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Recent Articles
1.
Sigar I, Schripsema J, Kelly K, Murthy A, Manam S, Ramsey K
BMC Res Notes . 2018 Jun; 11(1):361. PMID: 29880030
Objective: This study aims to eliminate Mycoplasma spp. contamination from laboratory stocks of Chlamydia spp. by in vivo passage or by plaque assay. Results: We have described two methods of...
2.
Ramsey K, Sigar I, Schripsema J, Townsend K, Barry R, Peters J, et al.
Pathog Dis . 2016 Jan; 74(3). PMID: 26733499
To determine if Chlamydia muridarum, or other chlamydiae, are enzootic in rodents, we probed a serum bank of wild Peromyscus spp. mice for immunoglobulin G-antibody reactivity to ultraviolet light-inactivated C....
3.
Jasper D, Sigar I, Schripsema J, Sainvil C, Smith C, Yeruva L, et al.
Pathog Dis . 2015 Feb; 73(1):1-12. PMID: 25673672
We have previously shown that Chlamydia muridarum has multiple genomic variants that concomitantly vary in their in vitro and in vivo phenotype. Herein, we used real-time polymerase chain reaction-based genotyping...
4.
Manam S, Thomas J, Li W, Maladore A, Schripsema J, Ramsey K, et al.
J Infect Dis . 2015 Jan; 211(12):2014-22. PMID: 25552370
Background: We demonstrated previously that tumor necrosis factor α (TNF-α)-producing Chlamydia-specific CD8(+) T cells cause oviduct pathological sequelae. Methods: In the current study, we used wild-type C57BL/6J (WT) mice with...
5.
Andrew D, Cochrane M, Schripsema J, Ramsey K, Dando S, OMeara C, et al.
PLoS One . 2013 Sep; 8(9):e76664. PMID: 24073293
IL-17 is believed to be important for protection against extracellular pathogens, where clearance is dependent on neutrophil recruitment and local activation of epithelial cell defences. However, the role of IL-17...
6.
Sigar I, Schripsema J, Wang Y, Clarke I, Cutcliffe L, Seth-Smith H, et al.
Pathog Dis . 2013 Sep; 70(1):61-9. PMID: 24022847
We hypothesized that the plasmid of urogenital isolates of Chlamydia trachomatis would modulate infectivity and virulence in a mouse model. To test this hypothesis, we infected female mice in the...
7.
Lee H, Schripsema J, Sigar I, Lacy S, Kasimos J, Murray C, et al.
FEMS Immunol Med Microbiol . 2010 Jul; 60(1):49-56. PMID: 20602634
We tested the hypothesis that a specific chemokine receptor, CXC chemokine receptor-2 (CXCR2), mediates acute inflammatory damage during chlamydial urogenital infection, which ultimately leads to the chronic sequelae of hydrosalpinx...
8.
Dixon R, Ramsey K, Schripsema J, Sanders K, Ward S
Biol Reprod . 2010 Apr; 83(2):244-53. PMID: 20427758
Chlamydia trachomatis is the most commonly reported infectious disease in the United States. In women, this infection can lead to pelvic inflammatory disease and cause ectopic pregnancy and tubal factor...
9.
Lee H, Schripsema J, Sigar I, Murray C, Lacy S, Ramsey K
FEMS Immunol Med Microbiol . 2010 Apr; 59(1):108-16. PMID: 20370824
Vigorous acute inflammatory responses accompany Chlamydia muridarum infections in mice and are positively correlated with adverse urogenital and respiratory tract infection outcomes in the mouse model. Thus, we tested the...
10.
Ramsey K, Sigar I, Schripsema J, Denman C, Bowlin A, Myers G, et al.
Infect Immun . 2009 May; 77(8):3284-93. PMID: 19470744
The mouse chlamydial pathogen Chlamydia muridarum has been used as a model organism for the study of human Chlamydia trachomatis urogenital and respiratory tract infections. To date, two commonly used...