Justin Demmerle
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Explore the profile of Justin Demmerle including associated specialties, affiliations and a list of published articles.
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12
Citations
698
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Recent Articles
1.
Hao S, Lee Y, Benhamou Goldfajn N, Flores E, Liang J, Fuehrer H, et al.
iScience
. 2024 May;
27(6):109927.
PMID: 38784009
YAP/TEAD signaling is essential for organismal development, cell proliferation, and cancer progression. As a transcriptional coactivator, how YAP activates its downstream target genes is incompletely understood. YAP forms biomolecular condensates...
2.
Demmerle J, Hao S, Cai D
Nucleus
. 2023 May;
14(1):2213551.
PMID: 37218279
Transcription is the fundamental process of gene expression, which in eukaryotes occurs within the complex physicochemical environment of the nucleus. Decades of research have provided extreme detail in the molecular...
3.
Demmerle J, Innocent C, North A, Ball G, Muller M, Miron E, et al.
Nat Protoc
. 2017 Apr;
12(5):988-1010.
PMID: 28406496
Linear 2D- or 3D-structured illumination microscopy (SIM or3D-SIM, respectively) enables multicolor volumetric imaging of fixed and live specimens with subdiffraction resolution in all spatial dimensions. However, the reliance of SIM...
4.
Kraus F, Miron E, Demmerle J, Chitiashvili T, Budco A, Alle Q, et al.
Nat Protoc
. 2017 Apr;
12(5):1011-1028.
PMID: 28406495
3D structured illumination microscopy (3D-SIM) is the super-resolution technique of choice for multicolor volumetric imaging. Here we provide a validated sample preparation protocol for labeling nuclei of cultured mammalian cells,...
5.
Ball G, Demmerle J, Kaufmann R, Davis I, Dobbie I, Schermelleh L
Sci Rep
. 2016 Feb;
6:20754.
PMID: 26847150
No abstract available.
6.
Hagen C, Dent K, Zeev-Ben-Mordehai T, Grange M, Bosse J, Whittle C, et al.
Cell
. 2015 Dec;
163(7):1692-701.
PMID: 26687357
Vesicular nucleo-cytoplasmic transport is becoming recognized as a general cellular mechanism for translocation of large cargoes across the nuclear envelope. Cargo is recruited, enveloped at the inner nuclear membrane (INM),...
7.
Ball G, Demmerle J, Kaufmann R, Davis I, Dobbie I, Schermelleh L
Sci Rep
. 2015 Nov;
5:15915.
PMID: 26525406
Three-dimensional structured illumination microscopy (3D-SIM) is a versatile and accessible method for super-resolution fluorescence imaging, but generating high-quality data is challenging, particularly for non-specialist users. We present SIMcheck, a suite...
8.
Demmerle J, Wegel E, Schermelleh L, Dobbie I
Methods
. 2015 Jul;
88:3-10.
PMID: 26164701
Resolution is a central concept in all imaging fields, and particularly in optical microscopy, but it can be easily misinterpreted. The mathematical definition of optical resolution was codified by Abbe,...
9.
Smeets D, Markaki Y, Schmid V, Kraus F, Tattermusch A, Cerase A, et al.
Epigenetics Chromatin
. 2014 Jul;
7:8.
PMID: 25057298
Background: A Xist RNA decorated Barr body is the structural hallmark of the compacted inactive X territory in female mammals. Using super-resolution three-dimensional structured illumination microscopy (3D-SIM) and quantitative image...
10.
Cerase A, Smeets D, Tang Y, Gdula M, Kraus F, Spivakov M, et al.
Proc Natl Acad Sci U S A
. 2014 Jan;
111(6):2235-40.
PMID: 24469834
In female mammals, one of the two X chromosomes is transcriptionally silenced to equalize X-linked gene dosage relative to XY males, a process termed X chromosome inactivation. Mechanistically, this is...