Jurgen Kreiter
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Explore the profile of Jurgen Kreiter including associated specialties, affiliations and a list of published articles.
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10
Citations
78
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Recent Articles
1.
Pohl E, Vazdar M, Kreiter J
Protein Sci
. 2025 Feb;
34(3):e70047.
PMID: 39969060
The mitochondrial ADP/ATP carrier (AAC, ANT), a member of the SLC25 family of solute carriers, plays a critical role in transporting purine nucleotides (ATP and ADP) as well as protons...
2.
Zuna K, Tyschuk T, Beikbaghban T, Sternberg F, Kreiter J, Pohl E
Acta Physiol (Oxf)
. 2024 Apr;
240(6):e14143.
PMID: 38577966
Aims: Metabolic reprogramming in cancer cells has been linked to mitochondrial dysfunction. The mitochondrial 2-oxoglutarate/malate carrier (OGC) has been suggested as a potential target for preventing cancer progression. Although OGC...
3.
Kreiter J, Tyschuk T, Pohl E
Biomolecules
. 2024 Jan;
14(1).
PMID: 38254621
Uncoupling protein 3 (UCP3) belongs to the mitochondrial carrier protein superfamily SLC25 and is abundant in brown adipose tissue (BAT), the heart, and muscles. The expression of UCP3 in tissues...
4.
Kreiter J, Skulj S, Brkljaca Z, Bardakji S, Vazdar M, Pohl E
Int J Mol Sci
. 2023 Sep;
24(18).
PMID: 37762012
Mitochondrial adenine nucleotide translocase (ANT) exchanges ADP for ATP to maintain energy production in the cell. Its protonophoric function in the presence of long-chain fatty acids (FA) is also recognized....
5.
Zuna K, Jovanovic O, Khailova L, Skulj S, Brkljaca Z, Kreiter J, et al.
Biomolecules
. 2021 Aug;
11(8).
PMID: 34439844
2,4-Dinitrophenol (DNP) is a classic uncoupler of oxidative phosphorylation in mitochondria which is still used in "diet pills", despite its high toxicity and lack of antidotes. DNP increases the proton...
6.
Kreiter J, Rupprecht A, Skulj S, Brkljaca Z, Zuna K, Knyazev D, et al.
Int J Mol Sci
. 2021 Apr;
22(5).
PMID: 33801254
Adenine nucleotide translocase (ANT) is a well-known mitochondrial exchanger of ATP against ADP. In contrast, few studies have shown that ANT also mediates proton transport across the inner mitochondrial membrane....
7.
Skulj S, Brkljaca Z, Kreiter J, Pohl E, Vazdar M
Int J Mol Sci
. 2021 Feb;
22(3).
PMID: 33530558
Molecular dynamics (MD) simulations of uncoupling proteins (UCP), a class of transmembrane proteins relevant for proton transport across inner mitochondrial membranes, represent a complicated task due to the lack of...
8.
Kreiter J, Beitz E, Pohl E
Biomolecules
. 2020 May;
10(5).
PMID: 32365477
Several mitochondrial proteins, such as adenine nucleotide translocase (ANT), aspartate/glutamate carrier, dicarboxylate carrier, and uncoupling proteins 2 and 3, are suggested to have dual transport functions. While the transport of...
9.
Kreiter J, Rupprecht A, Zimmermann L, Moschinger M, Rokitskaya T, Antonenko Y, et al.
Biophys J
. 2019 Nov;
117(10):1845-1857.
PMID: 31706565
Genipin, a natural compound from Gardenia jasminoides, is a well-known compound in Chinese medicine that is used for the treatment of cancer, inflammation, and diabetes. The use of genipin in...
10.
Kreiter J, Pohl E
J Vis Exp
. 2019 Jan;
(143).
PMID: 30663681
To date, more than 50% of all pharmacological drugs target the transport kinetics of membrane proteins. The electrophysiological characterization of membrane carrier proteins reconstituted in lipid bilayer membranes is a...