Anne Rupprecht
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Explore the profile of Anne Rupprecht including associated specialties, affiliations and a list of published articles.
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535
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Recent Articles
1.
Wendt F, Wittig F, Rupprecht A, Ramer R, Langer P, Emmert S, et al.
Cells
. 2023 Oct;
12(19).
PMID: 37830623
Skin cancer is the most common malignant disease worldwide and, therefore, also poses a challenge from a pharmacotherapeutic perspective. Derivatives of indirubin are an interesting option in this context. In...
2.
Rupprecht A, Theisen U, Wendt F, Frank M, Hinz B
Cancers (Basel)
. 2022 Jul;
14(13).
PMID: 35804909
Phytocannabinoids represent a promising approach in glioblastoma therapy. Previous work has shown that a combined treatment of glioblastoma cells with submaximal effective concentrations of psychoactive Δ-tetrahydrocannabinol (THC) and non-psychoactive cannabidiol...
3.
Riess C, Del Moral K, Fiebig A, Kaps P, Linke C, Hinz B, et al.
Cell Death Dis
. 2022 Jun;
13(6):555.
PMID: 35717443
Constitutive activation of cyclin-dependent kinases (CDKs) or arginine auxotrophy are hallmarks of Glioblastoma multiforme (GBM). The latter metabolic defect renders tumor cells vulnerable to arginine-depleting substances, such as arginine deiminase...
4.
Kreiter J, Rupprecht A, Skulj S, Brkljaca Z, Zuna K, Knyazev D, et al.
Int J Mol Sci
. 2021 Apr;
22(5).
PMID: 33801254
Adenine nucleotide translocase (ANT) is a well-known mitochondrial exchanger of ATP against ADP. In contrast, few studies have shown that ANT also mediates proton transport across the inner mitochondrial membrane....
5.
Kaltenecker D, Spirk K, Ruge F, Grebien F, Herling M, Rupprecht A, et al.
Mol Metab
. 2020 May;
40:101026.
PMID: 32473405
Objective: Increasing energy expenditure through activation of brown adipose tissue (BAT) thermogenesis is an attractive approach to counteract obesity. It is therefore essential to understand the molecular mechanisms that control...
6.
Moschinger M, Hilse K, Rupprecht A, Zeitz U, Erben R, Rulicke T, et al.
Biol Sex Differ
. 2019 Dec;
10(1):56.
PMID: 31806023
The prevalence and progression of many illnesses, such as neurodegenerative and cardiovascular diseases, obesity, and cancer, vary between women and men, often in an age-dependent manner. A joint hallmark of...
7.
Kreiter J, Rupprecht A, Zimmermann L, Moschinger M, Rokitskaya T, Antonenko Y, et al.
Biophys J
. 2019 Nov;
117(10):1845-1857.
PMID: 31706565
Genipin, a natural compound from Gardenia jasminoides, is a well-known compound in Chinese medicine that is used for the treatment of cancer, inflammation, and diabetes. The use of genipin in...
8.
Pohl E, Rupprecht A, Macher G, Hilse K
Front Physiol
. 2019 May;
10:470.
PMID: 31133866
Membrane uncoupling protein 3 (UCP3), a member of the mitochondrial uncoupling protein family, was discovered in 1997. UCP3's properties, such as its high homology to other mitochondrial carriers, especially to...
9.
Rupprecht A, Moldzio R, Modl B, Pohl E
Biochim Biophys Acta Bioenerg
. 2019 Mar;
1860(5):391-401.
PMID: 30885735
Mitochondrial uncoupling protein 2 (UCP2) is highly abundant in rapidly proliferating cells that utilize aerobic glycolysis, such as stem cells, cancer cells, and cells of the immune system. However, the...
10.
Hilse K, Rupprecht A, Egerbacher M, Bardakji S, Zimmermann L, Seiler Wulczyn A, et al.
Front Physiol
. 2018 Jul;
9:747.
PMID: 29988383
The involvement of mitochondrial uncoupling proteins 2 and 3 in the pathogenesis of cardiovascular diseases is widely acknowledged. However, contradictory reports show that the functions of UCP2/UCP3 are still disputed....