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Jurate Lasiene

Explore the profile of Jurate Lasiene including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 343
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Recent Articles
1.
Lasiene J, Komine O, Fujimori-Tonou N, Powers B, Endo F, Watanabe S, et al.
Acta Neuropathol Commun . 2016 Feb; 4:15. PMID: 26891847
Introduction: Increasing evidence implicates the role of the cell types surrounding motor neurons, such as interneurons and glial cells, in non-cell autonomous neurodegeneration of amyotrophic lateral sclerosis (ALS). C-boutons, the...
2.
Laing R, Lasiene J, Olavarria J
Biomed Res Int . 2013 Nov; 2013:592426. PMID: 24199194
It is known that retinal input is necessary for the normal development of striate cortex and its corticocortical connections, but there is little information on the role that retinal input...
3.
Powers B, Lasiene J, Plemel J, Shupe L, Perlmutter S, Tetzlaff W, et al.
J Neurosci . 2012 Apr; 32(15):5120-5. PMID: 22496557
Remyelination following spinal cord injury (SCI) is thought to be incomplete; demyelination is reported to persist chronically and is proposed as a compelling therapeutic target. Yet most reports do not...
4.
Stoll E, Habibi B, Mikheev A, Lasiene J, Massey S, Swanson K, et al.
Stem Cells . 2011 Sep; 29(12):2005-17. PMID: 21948688
Although new neurons are produced in the subventricular zone (SVZ) of the adult mammalian brain, fewer functional neurons are produced with increasing age. The age-related decline in neurogenesis has been...
5.
Lasiene J, Yamanaka K
Neurol Res Int . 2011 Jul; 2011:718987. PMID: 21766027
Amyotrophic lateral sclerosis (ALS) is an adult motor neuron disease characterized by premature death of upper and lower motor neurons. Two percent of ALS cases are caused by the dominant...
6.
Kwon E, Lasiene J, Jacobson B, Park I, Horner P, Pun S
Biomaterials . 2009 Dec; 31(8):2417-24. PMID: 20004466
Targeted gene therapy can potentially minimize undesirable off-target toxicity due to specific delivery. Neuron-specific gene delivery in the central nervous system is challenging because neurons are non-dividing and also outnumbered...
7.
Olavarria J, Laing R, Hiroi R, Lasiene J
Biol Res . 2009 Jul; 41(4):413-24. PMID: 19621122
Visual callosal fibers link cortical loci in opposite hemispheres that represent the same visual field but whose locations are not mirror-symmetric with respect to the brain midline. Presence of the...
8.
Lasiene J, Matsui A, Sawa Y, Wong F, Horner P
Aging Cell . 2009 Apr; 8(2):201-13. PMID: 19338498
Aging is associated with many functional and morphological central nervous system changes. It is important to distinguish between changes created by normal aging and those caused by disease. In the...
9.
Lasaite L, Lasiene J, Kazanavicius G, Gostautas A
Medicina (Kaunas) . 2009 Mar; 45(2):85-94. PMID: 19289898
The aim of the study was to evaluate associations of emotional state and quality of life with lipid concentration, duration of the disease, and the way of treating the disease...
10.
Lasiene J, Shupe L, Perlmutter S, Horner P
J Neurosci . 2008 Apr; 28(15):3887-96. PMID: 18400887
The pattern of remyelination after traumatic spinal cord injury remains elusive, with animal and human studies reporting partial to complete demyelination followed by incomplete remyelination. In the present study, we...