Koji Yamanaka
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Explore the profile of Koji Yamanaka including associated specialties, affiliations and a list of published articles.
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92
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9974
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Recent Articles
1.
Fuma K, Iitani Y, Imai K, Ushida T, Tano S, Yoshida K, et al.
Commun Biol
. 2025 Jan;
8(1):75.
PMID: 39824932
Histological chorioamnionitis (HCA) is a form of maternal immune activation (MIA) linked to an increased risk of neurodevelopmental disorders in offspring. Our previous study identified neurodevelopmental impairments in an MIA...
2.
Horiuchi M, Watanabe S, Komine O, Takahashi E, Kaneko K, Itohara S, et al.
Acta Neuropathol Commun
. 2024 Nov;
12(1):184.
PMID: 39605053
Nuclear clearance and cytoplasmic aggregation of TAR DNA-binding protein of 43 kDa (TDP-43) are pathological hallmarks of amyotrophic lateral sclerosis (ALS) and its pathogenic mechanism is mediated by both loss-of-function...
3.
Sobue A, Komine O, Endo F, Kakimi C, Miyoshi Y, Kawade N, et al.
Cell Death Dis
. 2024 Nov;
15(11):858.
PMID: 39587077
Alzheimer's disease (AD) is the most common form of dementia and is characterized by the accumulation of amyloid β (Aβ) and phosphorylated tau. Neuroinflammation, mainly mediated by glial activation, plays...
4.
Hirayama T, Morioka H, Sugisawa T, Shibukawa M, Ebina J, Hanashiro S, et al.
J Clin Neurosci
. 2024 Aug;
128:110778.
PMID: 39168060
Spinal and bulbar muscular atrophy (SBMA) progressively impairs gait function, resulting in the need for patients to use a wheelchair approximately 20 years after onset. No reports have investigated the...
5.
Fujisawa H, Watanabe T, Komine O, Fuse S, Masaki M, Iwata N, et al.
Free Radic Biol Med
. 2024 Aug;
223:458-472.
PMID: 39155026
Hyponatremia is the most common clinical electrolyte disorder. Chronic hyponatremia has been recently reported to be associated with falls, fracture, osteoporosis, neurocognitive impairment, and mental manifestations. In the treatment of...
6.
Watanabe S, Amporndanai K, Awais R, Latham C, Awais M, ONeill P, et al.
Sci Rep
. 2024 May;
14(1):12118.
PMID: 38802492
Amyotrophic lateral sclerosis (ALS) selectively affects motor neurons. SOD1 is the first causative gene to be identified for ALS and accounts for at least 20% of the familial (fALS) and...
7.
Leventoux N, Morimoto S, Ishikawa M, Nakamura S, Ozawa F, Kobayashi R, et al.
Acta Neuropathol
. 2024 May;
147(1):84.
PMID: 38750212
Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC), a rare and complex neurological disorder, is predominantly observed in the Western Pacific islands, including regions of Japan, Guam, and Papua. This enigmatic condition continues...
8.
Wang T, Sobue A, Watanabe S, Komine O, Saido T, Saito T, et al.
J Neuroinflammation
. 2024 Feb;
21(1):55.
PMID: 38383481
Background: Neuroinflammation substantially contributes to the pathology of Alzheimer's disease (AD), the most common form of dementia. Studies have reported that nuclear factor erythroid 2-related factor 2 (Nrf2) attenuates neuroinflammation...
9.
Komine O, Ohnuma S, Hinohara K, Hara Y, Shimada M, Akashi T, et al.
iScience
. 2024 Feb;
27(2):108872.
PMID: 38318390
Recent single-cell analyses have revealed the complexity of microglial heterogeneity in brain development, aging, and neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS). Disease-associated microglia (DAMs) have been identified in...
10.
Tsagakis I, Yamanaka K
FEBS Open Bio
. 2024 Jan;
14(2):162-164.
PMID: 38217066
Koji Yamanaka is a Professor at the Research Institute of Environmental Medicine at Nagoya University of Japan. His research interests lie in understanding the mechanism of onset and progression of...