Junkui Shang
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Explore the profile of Junkui Shang including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
207
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Recent Articles
1.
Xia M, Gao C, Shang J, Li D, Yang A, Zang W, et al.
Eur J Med Res
. 2025 Mar;
30(1):157.
PMID: 40055834
Background/purpose: GRN mutations act as causative factors in patients with FTD clinical phenotype or FTD pathology and exhibit high clinical heterogeneity. The discovery of these mutations and the analysis of...
2.
Li Q, Sandoval A, Moth J, Shang J, Liew J, Dunn T, et al.
Sci Transl Med
. 2024 Sep;
16(766):eadn7095.
PMID: 39321270
Spinal cord injury (SCI) results in acute damage and triggers secondary injury responses with sustained neuronal loss and dysfunction. However, the underlying mechanisms for these delayed neuronal pathologies are not...
3.
Wang W, Gong Z, Wang Y, Zhao Y, Lu Y, Sun R, et al.
J Alzheimers Dis
. 2024 Jul;
100(4):1299-1314.
PMID: 39031358
Background: Cerebral autosomal-dominant arteriopathy with subcortical infarction and leukoencephalopathy (CADASIL) is an inherited small-vessel disease that affects the white matter of the brain. Recent studies have confirmed that the deposition...
4.
Zhu L, Shang J, Li Y, Zhang Z, Fu P, Zong Y, et al.
Stroke
. 2024 Jun;
55(8):2126-2138.
PMID: 38920054
Background: Dendritic cells (DCs) regulate the immune response associated with T lymphocytes, but their role in stroke remains unclear. In this study, we investigated the causal relationship between DCs and...
5.
Zhang H, Shang J, Li W, Gao D, Zhang J
ACS Chem Neurosci
. 2024 May;
15(10):2028-2041.
PMID: 38710594
Chronic cerebral hypoperfusion (CCH)-triggered blood-brain barrier (BBB) dysfunction is a core pathological change occurring in vascular dementia (VD). Despite the recent advances in the exploration of the structural basis of...
6.
Ma L, Wang F, Chen S, Wang S, Wang Z, Xia M, et al.
Neuromolecular Med
. 2024 Mar;
26(1):6.
PMID: 38504005
Familial Alzheimer's disease (AD) is a rare disease caused by autosomal-dominant mutations. APP (encoding amyloid precursor protein), PSEN1 (encoding presenilin 1), and PSEN2 (encoding presenilin 2) are the most common...
7.
Gao C, Shang J, Sun Z, Xia M, Gao D, Sun R, et al.
Mol Neurobiol
. 2023 Dec;
61(8):5047-5070.
PMID: 38159198
Alzheimer's disease (AD) is an age-related progressive neurodegenerative disease, and approximately 10% of AD cases are early-onset familial AD (EOFAD), which is mainly linked to point mutations in genes encoding...
8.
Shang J, Li W, Zhang H, Wang W, Liu N, Gao D, et al.
Biomed Pharmacother
. 2023 Dec;
170:115778.
PMID: 38141279
Blood-brain barrier (BBB) dysfunction plays a pivotal role in the pathology of chronic cerebral hypoperfusion (CCH)-related neurodegenerative diseases. Continuous endothelial cells (EC) that line the blood vessels of the brain...
9.
Zou J, Wang F, Gong Z, Wang R, Chen S, Zhang H, et al.
Front Genet
. 2023 Apr;
14:1110307.
PMID: 37051597
Spinocerebellar ataxias 36 (SCA36) is the neurodegenerative disease caused by the GGCCTG Hexanucleotide repeat expansions in , which is too long to sequence using short-read sequencing. Single molecule real time...
10.
Sun R, Shang J, Yan X, Zhao J, Wang W, Wang W, et al.
J Alzheimers Dis
. 2023 Jan;
91(4):1541-1555.
PMID: 36641679
Background: Chronic cerebral hypoperfusion (CCH) is associated with neuronal loss and blood-brain barrier (BBB) impairment in vascular dementia (VaD). However, the relationship and the molecular mechanisms between BBB dysfunction and...