Junkui Shang
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Explore the profile of Junkui Shang including associated specialties, affiliations and a list of published articles.
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24
Citations
207
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0
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Recent Articles
11.
Yan X, Shang J, Wang R, Wang F, Zhang J
J Biomed Res
. 2022 Sep;
36(5):353-357.
PMID: 36165325
Cerebral small vessel disease (CSVD) is a leading cause of stroke and dementia. As the most common type of inherited CSVD, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy...
12.
Effects of different regional cerebral blood flow on white matter hyperintensity in CADASIL patients
Wang R, Zhang J, Shang J, Wang F, Yan X
J Biomed Res
. 2022 Sep;
36(5):368-374.
PMID: 36165295
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an early-onset inherited small vessel disease. Decreased cerebral blood flow (CBF) may contribute to white matter hyperintensity (WMH) severity...
13.
Novel PSEN1 (P284S) Mutation Causes Alzheimer's Disease with Cerebellar Amyloid β-Protein Deposition
Xia M, Gao C, Wang H, Shang J, Liu R, You Y, et al.
Curr Alzheimer Res
. 2022 Jul;
19(7):523-529.
PMID: 35850649
Background/objective: AD-associated PSEN1 mutations exhibit high clinical heterogeneity. The discovery of these mutations and the analysis of their associations with cases such as EOAD should be critical to understanding AD's...
14.
Zhao C, Rao J, Duan H, Hao P, Shang J, Fan Y, et al.
Signal Transduct Target Ther
. 2022 Jun;
7(1):184.
PMID: 35710784
Spinal cord injury (SCI) is a severe damage usually leading to limb dysesthesia, motor dysfunction, and other physiological disability. We have previously shown that NT3-chitosan could trigger an acute SCI...
15.
Li W, Zou J, Shang J, Gao C, Sun R, Liu R, et al.
Front Neurosci
. 2022 May;
16:850857.
PMID: 35573303
The blood-brain barrier (BBB) comprises a single layer of endothelial cells and maintains a safe and homeostatic environment for proper neuronal function and synaptic transmission. BBB is not a discrete...
16.
Liu R, Gao C, Shang J, Sun R, Wang W, Li W, et al.
J Alzheimers Dis
. 2022 Jan;
86(1):67-81.
PMID: 35001891
Background: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) caused by NOTCH3 mutations is the most common monogenic hereditary pattern of cerebral small vessel disease. The aggregation of...
17.
Zhang J, Shang J, Wang F, Huo X, Sun R, Ren Z, et al.
Clin Epigenetics
. 2022 Jan;
14(1):2.
PMID: 34983647
Background: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a typical neurodegenerative disease associated with mitochondrial dysfunction. Methylation of the D-loop region and mitochondrial DNA copy number...
18.
Zhang H, Qin X, Shi Y, Gao X, Wang F, Wang H, et al.
Neurogenetics
. 2021 May;
22(3):187-194.
PMID: 33963955
Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is caused by biallelic HTRA1 pathogenic variants. Recent studies have shown that heterozygous HTRA1 mutations are associated with autosomal dominant...
19.
Sun Z, Gao C, Gao D, Sun R, Li W, Wang F, et al.
Fluids Barriers CNS
. 2021 May;
18(1):21.
PMID: 33952281
Background: Chronic cerebral hypoperfusion (CCH) is the leading cause of cerebral small vessel disease (CSVD). CCH is strongly associated with blood-brain barrier (BBB) dysfunction and white matter lesions (WMLs) in...
20.
Gao D, Shang J, Sun R, Shi Y, Jiang H, Ma M, et al.
J Alzheimers Dis
. 2021 Mar;
81(1):221-229.
PMID: 33749657
Background: Exosomes are nano-sized extracellular vesicles which are secreted by cells and usually found in body fluids. Previous research has shown that exosomal secretion and autophagy-lysosomal pathway synergistically participates in...