Junbin Qian
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Explore the profile of Junbin Qian including associated specialties, affiliations and a list of published articles.
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30
Citations
2056
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Recent Articles
21.
Qian J, Gelens L, Bollen M
Bioessays
. 2019 Feb;
41(3):e1800217.
PMID: 30730051
Timers and sensors are common devices that make our daily life safer, more convenient, and more efficient. In a cellular context, they arguably play an even more crucial role as...
22.
Dong L, Qian J, Chen F, Fan Y, Long J
J Cell Biochem
. 2019 Jan;
120(4):4851-4862.
PMID: 30623482
Mounting evidence has demonstrated that long noncoding RNAs (lncRNAs) are dysregulated and implicated in the occurrence and development of a wide range of human malignancies. LINC00461, a novel cancer-related lncRNA,...
23.
Qian J, Garcia-Gimeno M, Beullens M, Manzione M, Van der Hoeven G, Igual J, et al.
Mol Cell
. 2017 Nov;
68(4):715-730.e5.
PMID: 29129638
The spindle assembly checkpoint (SAC) generates a diffusible protein complex that prevents anaphase until all chromosomes are properly attached to spindle microtubules. A key step in SAC initiation is the...
24.
Gelens L, Qian J, Bollen M, Saurin A
Trends Cell Biol
. 2017 Nov;
28(1):6-21.
PMID: 29089159
Kinases and phosphatases work antagonistically to control the behaviour of individual substrate molecules. This can be incorrectly extrapolated to imply that they also work antagonistically on the signals or processes...
25.
De Munter S, Gornemann J, Derua R, Lesage B, Qian J, Heroes E, et al.
FEBS Lett
. 2016 Dec;
591(2):415-424.
PMID: 28032891
The biotin identification (BioID) protocol uses a mutant of the biotin ligase BirA (BirA*) fused to a protein-of-interest to biotinylate proximate proteins in intact cells. Here, we show that two...
26.
Qian J, Beullens M, Huang J, De Munter S, Lesage B, Bollen M
Nat Commun
. 2015 Dec;
6:10215.
PMID: 26674376
RepoMan is a scaffold for signalling by mitotic phosphatases at the chromosomes. During (pro)metaphase, RepoMan-associated protein phosphatases PP1 and PP2A-B56 regulate the chromosome targeting of Aurora-B kinase and RepoMan, respectively....
27.
Qian J, Winkler C, Bollen M
Curr Opin Cell Biol
. 2013 Jul;
25(6):697-703.
PMID: 23849679
Faithful progression through mitosis is critically dependent on the timely phosphorylation and dephosphorylation of a host of proteins. The involved protein kinases and phosphatases are embedded in interconnected feedback and...
28.
Qian J, Beullens M, Lesage B, Bollen M
Curr Biol
. 2013 Jun;
23(12):1136-43.
PMID: 23746640
Aurora B is the catalytic subunit of the chromosomal passenger complex (CPC), which coordinates mitotic processes through phosphorylation of key regulatory proteins. In prometaphase, the CPC is enriched at the...
29.
Chatterjee J, Beullens M, Sukackaite R, Qian J, Lesage B, Hart D, et al.
Angew Chem Int Ed Engl
. 2012 Sep;
51(40):10054-9.
PMID: 22962028
No abstract available.
30.
Lesage B, Qian J, Bollen M
Curr Biol
. 2011 Nov;
21(21):R898-903.
PMID: 22075433
The spindle checkpoint is a mitotic surveillance mechanism that delays anaphase until all sister chromatids are correctly attached to microtubules from opposite poles. Recent studies reveal that protein kinase Aurora...