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Julio Aliberti

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Articles 46
Citations 2279
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Recent Articles
21.
Kuribayashi J, Bombardieri C, Baracho G, Aliberti J, Machado F, Kalil J, et al.
Mol Immunol . 2008 Mar; 45(10):2990-7. PMID: 18325593
Common variable immunodeficiency (CVID) is a primary immunodeficiency characterized by hypogammaglobulinemia and recurrent infections. Herein we addressed the role of unfolded protein response (UPR) in the pathogenesis of the disease....
22.
Bafica A, Feng C, Santiago H, Aliberti J, Cheever A, Thomas K, et al.
J Immunol . 2007 Oct; 179(8):5514-22. PMID: 17911638
LRG47/Irgm1, a 47-kDa IFN-inducible GTPase, plays a major role in regulating host resistance as well as the hemopoietic response to intracellular pathogens. LRG47 expression in macrophages has been shown previously...
23.
Machado F, Aliberti J
Immunol Res . 2006 Dec; 35(3):209-18. PMID: 17172647
During Toxoplasma gondii infection pro-inflammatory mediators such as IL-12, IFN-gamma, and TNF are essential in controlling parasite growth. Those factors, however, can be detrimental to the host if produced in...
24.
Liu C, Fan Y, Dias A, Esper L, Corn R, Bafica A, et al.
J Immunol . 2006 Jun; 177(1):31-5. PMID: 16785494
A powerful IFN-gamma response is triggered upon infection with the protozoan parasite, Toxoplasma gondii. Several cell populations, including dendritic cells (DCs), macrophages, and neutrophils, produce IL-12, a key cytokine for...
25.
Machado F, Johndrow J, Esper L, Dias A, Bafica A, Serhan C, et al.
Nat Med . 2006 Jan; 12(3):330-4. PMID: 16415877
Control of inflammation is crucial to prevent damage to the host during infection. Lipoxins and aspirin-triggered lipoxins are crucial modulators of proinflammatory responses; however, their intracellular mechanisms have not been...
26.
Santiago H, Feng C, Bafica A, Roffe E, Arantes R, Cheever A, et al.
J Immunol . 2005 Dec; 175(12):8165-72. PMID: 16339555
IFN-gamma is known to be required for host control of intracellular Trypanosoma cruzi infection in mice, although the basis of its protective function is poorly understood. LRG-47 is an IFN-inducible...
27.
Huang L, Ishii K, Akira S, Aliberti J, Golding B
J Immunol . 2005 Sep; 175(6):3964-70. PMID: 16148144
In this report we provide evidence, for the first time, that bacterial DNA in the context of heat-killed Brucella abortus (HKBA) engages TLR9 in dendritic cells (DC), resulting in a...
28.
Aliberti J, Bafica A
Prostaglandins Leukot Essent Fatty Acids . 2005 Jun; 73(3-4):283-8. PMID: 15982863
Lipoxins play a key role in controlling potent pro-inflammatory responses triggered by infection with pathogens, such as Toxoplasma gondii and Mycobacterium tuberculosis. In order to contain microbial dissemination, infected hosts...
29.
Bafica A, Scanga C, Serhan C, Machado F, White S, Sher A, et al.
J Clin Invest . 2005 Jun; 115(6):1601-6. PMID: 15931391
Th1 type cytokine responses are critical in the control of Mycobacterium tuberculosis infection. Recent findings indicate that 5-lipoxygenase-dependent (5-LO-dependent) lipoxins regulate host IL-12 production in vivo. Here, we establish lipoxins...
30.
Arita M, Bianchini F, Aliberti J, Sher A, Chiang N, Hong S, et al.
J Exp Med . 2005 Mar; 201(5):713-22. PMID: 15753205
The essential fatty acid eicosapentaenoic acid (EPA) present in fish oils displays beneficial effects in a range of human disorders associated with inflammation including cardiovascular disease. Resolvin E1 (RvE1), a...