Julien Renou
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Explore the profile of Julien Renou including associated specialties, affiliations and a list of published articles.
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12
Citations
269
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Recent Articles
1.
Renou J, Li D, Lu J, Zhang B, Gineau E, Ye Y, et al.
Plant Physiol
. 2024 Jun;
196(1):124-136.
PMID: 38833284
P4B (2-phenyl-1-[4-(6-(piperidin-1-yl) pyridazin-3-yl) piperazin-1-yl] butan-1-one) is a novel cellulose biosynthesis inhibitor (CBI) discovered in a screen for molecules to identify inhibitors of Arabidopsis (Arabidopsis thaliana) seedling growth. Growth and cellulose...
2.
Valette N, Renou J, Boutilliat A, Fernandez-Gonzalez A, Gautier V, Silar P, et al.
Environ Microbiol
. 2021 Jan;
23(3):1594-1607.
PMID: 33393164
Secreted proteins are key players in fungal physiology and cell protection against external stressing agents and antifungals. Oak stress-induced protein 1 (OSIP1) is a fungal-specific protein with unknown function. By...
3.
Gonneau M, Desprez T, Martin M, Doblas V, Bacete L, Miart F, et al.
Curr Biol
. 2018 Jul;
28(15):2452-2458.e4.
PMID: 30057301
The growth of plants, like that of other walled organisms, depends on the ability of the cell wall to yield without losing its integrity. In this context, plant cells can...
4.
Zorbaz T, Braiki A, Marakovic N, Renou J, De La Mora E, Macek Hrvat N, et al.
Chemistry
. 2018 Apr;
24(38):9675-9691.
PMID: 29672968
A new series of 3-hydroxy-2-pyridine aldoxime compounds have been designed, synthesised and tested in vitro, in silico, and ex vivo as reactivators of human acetylcholinesterase (hAChE) and butyrylcholinesterase (hBChE) inhibited...
5.
Vivoli M, Renou J, Chevalier A, Norville I, Diaz S, Juli C, et al.
Anal Biochem
. 2017 Aug;
536:59-68.
PMID: 28803887
Prolyl-peptidyl isomerases (PPIases) are enzymes that are found in all living organisms. They form an essential part of the cellular protein folding homeostasis machinery. PPIases are associated with many important...
6.
Kliachyna M, Santoni G, Nussbaum V, Renou J, Sanson B, Colletier J, et al.
Eur J Med Chem
. 2014 Apr;
78:455-67.
PMID: 24704618
A series of new uncharged functional acetylcholinesterase (AChE) reactivators including heterodimers of tetrahydroacridine with 3-hydroxy-2-pyridine aldoximes and amidoximes has been synthesized. These novel molecules display in vitro reactivation potencies towards...
7.
Renou J, Loiodice M, Arboleas M, Baati R, Jean L, Nachon F, et al.
Chem Commun (Camb)
. 2014 Mar;
50(30):3947-50.
PMID: 24599312
Two promising uncharged reactivators for inhibited human BChE and AChE have been described. These compounds show an ability to reactivate VX-inhibited BChE largely superior to those of known pyridinium aldoximes....
8.
Mercey G, Renou J, Verdelet T, Kliachyna M, Baati R, Gillon E, et al.
J Med Chem
. 2012 Nov;
55(23):10791-5.
PMID: 23148598
Pyridinium and bis-pyridinium aldoximes are used as antidotes to reactivate acetylcholinesterase (AChE) inhibited by organophosphorus nerve agents. Herein, we described a series of nine nonquaternary phenyltetrahydroisoquinoline-pyridinaldoxime conjugates more efficient than...
9.
Renou J, Mercey G, Verdelet T, Paunescu E, Gillon E, Arboleas M, et al.
Chem Biol Interact
. 2012 Nov;
203(1):81-4.
PMID: 23111374
Organophosphorus nerve agents (OPNAs) are highly toxic compounds that represent a threat to both military and civilian populations. They cause an irreversible inhibition of acetylcholinesterase (AChE), by the formation of...
10.
Mercey G, Verdelet T, Renou J, Kliachyna M, Baati R, Nachon F, et al.
Acc Chem Res
. 2012 Feb;
45(5):756-66.
PMID: 22360473
Since the September 11, 2001, terrorist attacks in the United States, the specter of a chemical threat against civilian populations has renewed research interest in chemical warfare agents, their mechanisms...