Julien Come
Overview
Explore the profile of Julien Come including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
413
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0
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Recent Articles
1.
Strathmann E, Holker I, Tschernoster N, Hosseinibarkooie S, Come J, Martinat C, et al.
Am J Hum Genet
. 2023 Feb;
110(3):442-459.
PMID: 36812914
Dysregulated Plastin 3 (PLS3) levels associate with a wide range of skeletal and neuromuscular disorders and the most common types of solid and hematopoietic cancer. Most importantly, PLS3 overexpression protects...
2.
Maury Y, Poydenot P, Brinon B, Lesueur L, Gide J, Roqueviere S, et al.
iScience
. 2019 Jan;
11:258-271.
PMID: 30639849
There is currently no treatment for myotonic dystrophy type 1 (DM1), the most frequent myopathy of genetic origin. This progressive neuromuscular disease is caused by nuclear-retained RNAs containing expanded CUG...
3.
Powis R, Karyka E, Boyd P, Come J, Jones R, Zheng Y, et al.
JCI Insight
. 2016 Oct;
1(11):e87908.
PMID: 27699224
The autosomal recessive neuromuscular disease spinal muscular atrophy (SMA) is caused by loss of survival motor neuron (SMN) protein. Molecular pathways that are disrupted downstream of SMN therefore represent potentially...
4.
Vallot C, Ouimette J, Makhlouf M, Feraud O, Pontis J, Come J, et al.
Cell Stem Cell
. 2015 Apr;
16(5):533-46.
PMID: 25921272
Human pluripotent stem cells (hPSCs) display extensive epigenetic instability, particularly on the X chromosome. In this study, we show that, in hPSCs, the inactive X chromosome has a specific heterochromatin...
5.
Maury Y, Come J, Piskorowski R, Salah-Mohellibi N, Chevaleyre V, Peschanski M, et al.
Nat Biotechnol
. 2014 Nov;
33(1):89-96.
PMID: 25383599
Specification of cell identity during development depends on exposure of cells to sequences of extrinsic cues delivered at precise times and concentrations. Identification of combinations of patterning molecules that control...
6.
Polentes J, Jendelova P, Cailleret M, Braun H, Romanyuk N, Tropel P, et al.
Cell Transplant
. 2012 Aug;
21(12):2587-602.
PMID: 22889472
Human induced pluripotent stem cells (hiPSCs) are a most appealing source for cell replacement therapy in acute brain lesions. We evaluated the potential of hiPSC therapy in stroke by transplanting...
7.
Tropel P, Tournois J, Come J, Varela C, Moutou C, Fragner P, et al.
In Vitro Cell Dev Biol Anim
. 2010 Mar;
46(3-4):376-85.
PMID: 20217271
Pre-implantation genetic diagnosis allows the characterisation of embryos that carry a gene responsible for a severe monogenic disease and to transfer to the mother's uterus only the unaffected one(s). The...
8.
Come J, Nissan X, Aubry L, Tournois J, Girard M, Perrier A, et al.
Tissue Eng Part C Methods
. 2008 Aug;
14(4):289-98.
PMID: 18710335
In parallel to the active search for therapeutic and industrial applications of human embryonic stem cells (hESCs), designing automated means of producing those cells is a timely goal. Slow-turning lateral...