Michel Cailleret
Overview
Explore the profile of Michel Cailleret including associated specialties, affiliations and a list of published articles.
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16
Citations
309
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Recent Articles
1.
Louessard M, Cailleret M, Jarrige M, Bigarreau J, Lenoir S, Dufour N, et al.
J Huntingtons Dis
. 2024 Mar;
13(1):41-53.
PMID: 38427495
Background: Mutations in the Huntingtin (HTT) gene cause Huntington's disease (HD), a neurodegenerative disorder. As a scaffold protein, HTT is involved in numerous cellular functions, but its normal and pathogenic...
2.
Frank E, Cailleret M, Nelep C, Fragner P, Polentes J, Herardot E, et al.
Stem Cell Res Ther
. 2023 Apr;
14(1):110.
PMID: 37106426
Background: CRISPR/Cas9 editing systems are currently used to generate mutations in a particular gene to mimic a genetic disorder in vitro. Such "disease in a dish" models based on human...
3.
Pourtoy-Brasselet S, Sciauvaud A, Boza-Moran M, Cailleret M, Jarrige M, Polveche H, et al.
Am J Hum Genet
. 2021 Oct;
108(11):2171-2185.
PMID: 34699745
Recent studies indicate that neurodegenerative processes that appear during childhood and adolescence in individuals with Wolfram syndrome (WS) occur in addition to early brain development alteration, which is clinically silent....
4.
Merien A, Tahraoui-Bories J, Cailleret M, Dupont J, Leteur C, Polentes J, et al.
Hum Mol Genet
. 2021 Jul;
31(1):41-56.
PMID: 34312665
Alternative splicing has emerged as a fundamental mechanism for the spatiotemporal control of development. A better understanding of how this mechanism is regulated has the potential not only to elucidate...
5.
Ruillier V, Tournois J, Boissart C, Lasbareilles M, Mahe G, Chatrousse L, et al.
JCI Insight
. 2020 Jan;
5(4).
PMID: 31990683
Lesch-Nyhan disease (LND) is a rare monogenic disease caused by deficiency of the salvage pathway enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT). LND is characterized by severe neuropsychiatric symptoms that currently cannot be...
6.
Barrault L, Gide J, Qing T, Lesueur L, Tost J, Denis J, et al.
Cells
. 2019 Nov;
8(12).
PMID: 31779280
Substantial variations in differentiation properties have been reported among human pluripotent cell lines (hPSC), which could affect their utility and clinical safety. We characterized the variable osteogenic capacity observed between...
7.
Sari-Hassoun M, Clement M, Hamdi I, Bollot G, Bauvais C, Joshi V, et al.
Biochem Pharmacol
. 2015 Dec;
102:45-63.
PMID: 26707799
Cucurbitacins are cytotoxic triterpenoid sterols isolated from plants. One of their earliest cellular effect is the aggregation of actin associated with blockage of cell migration and division that eventually lead...
8.
Gauthier M, Marteyn A, Denis J, Cailleret M, Giraud-Triboult K, Aubert S, et al.
Hum Mol Genet
. 2013 Aug;
22(25):5188-98.
PMID: 23922231
Myotonic dystrophy type 1 (DM1) is an RNA-mediated disorder caused by a non-coding CTG repeat expansion that, in particular, provokes functional alteration of CUG-binding proteins. As a consequence, several genes...
9.
Charbord J, Poydenot P, Bonnefond C, Feyeux M, Casagrande F, Brinon B, et al.
Stem Cells
. 2013 May;
31(9):1816-28.
PMID: 23712629
Decreased expression of neuronal genes such as brain-derived neurotrophic factor (BDNF) is associated with several neurological disorders. One molecular mechanism associated with Huntington disease (HD) is a discrete increase in...
10.
Polentes J, Jendelova P, Cailleret M, Braun H, Romanyuk N, Tropel P, et al.
Cell Transplant
. 2012 Aug;
21(12):2587-602.
PMID: 22889472
Human induced pluripotent stem cells (hiPSCs) are a most appealing source for cell replacement therapy in acute brain lesions. We evaluated the potential of hiPSC therapy in stroke by transplanting...