Julie C Mitchell
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Explore the profile of Julie C Mitchell including associated specialties, affiliations and a list of published articles.
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47
Citations
900
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Recent Articles
21.
Adamji R, Bryant C, Ahluwalia M, Mitchell J
Dent Update
. 2017 Nov;
43(6):545-8.
PMID: 29148648
Isolated bilateral macrodontia of the mandibular second premolars is a rare condition. We believe that the case reported here is the first in which isolated bilateral macrodontia of the mandibular...
22.
Sukumar S, Zhu X, Ericksen S, Mitchell J
Bioinformatics
. 2016 Jun;
32(18):2853-5.
PMID: 27259543
Unlabelled: : Protein-nucleic acid interactions are among the most important intermolecular interactions in the regulation of cellular events. Identifying residues involved in these interactions from protein structure alone is an...
23.
Cimermancic P, Weinkam P, Rettenmaier T, Bichmann L, Keedy D, Woldeyes R, et al.
J Mol Biol
. 2016 Feb;
428(4):709-719.
PMID: 26854760
Many proteins have small-molecule binding pockets that are not easily detectable in the ligand-free structures. These cryptic sites require a conformational change to become apparent; a cryptic site can therefore...
24.
Alsop J, Mitchell J
Proteins
. 2015 Mar;
83(11):1940-6.
PMID: 25740680
Proteins are essential elements of biological systems, and their function typically relies on their ability to successfully bind to specific partners. Recently, an emphasis of study into protein interactions has...
25.
Lohman D, Forouhar F, Beebe E, Stefely M, Minogue C, Ulbrich A, et al.
Proc Natl Acad Sci U S A
. 2014 Oct;
111(44):E4697-705.
PMID: 25339443
Coenzyme Q (CoQ) is an isoprenylated quinone that is essential for cellular respiration and is synthesized in mitochondria by the combined action of at least nine proteins (COQ1-9). Although most...
26.
Structural analysis and modeling reveals new mechanisms governing ESCRT-III spiral filament assembly
Shen Q, Schuh A, Zheng Y, Quinney K, Wang L, Hanna M, et al.
J Cell Biol
. 2014 Sep;
206(6):763-77.
PMID: 25202029
The scission of biological membranes is facilitated by a variety of protein complexes that bind and manipulate lipid bilayers. ESCRT-III (endosomal sorting complex required for transport III) filaments mediate membrane...
27.
Lensink M, Moal I, Bates P, Kastritis P, Melquiond A, Karaca E, et al.
Proteins
. 2013 Oct;
82(4):620-32.
PMID: 24155158
We report the first assessment of blind predictions of water positions at protein-protein interfaces, performed as part of the critical assessment of predicted interactions (CAPRI) community-wide experiment. Groups submitting docking...
28.
Zhu X, Ericksen S, Demerdash O, Mitchell J
Proteins
. 2013 Sep;
81(12):2221-8.
PMID: 24038640
We describe methods and results for four new types of challenge in the Critical Assessment of PRedicted Interactions (CAPRI). Two new challenges asked predictors to create models related to protein...
29.
Pattnaik B, Tokarz S, Asuma M, Schroeder T, Sharma A, Mitchell J, et al.
PLoS One
. 2013 Aug;
8(8):e71744.
PMID: 23977131
Snowflake Vitreoretinal Degeneration (SVD) is associated with the R162W mutation of the Kir7.1 inwardly-rectifying potassium channel. Kir7.1 is found at the apical membrane of Retinal Pigment Epithelial (RPE) cells, adjacent...
30.
Zhu X, Ericksen S, Mitchell J
Nucleic Acids Res
. 2013 Jul;
41(16):e160.
PMID: 23873960
In this study, we present the DNA-Binding Site Identifier (DBSI), a new structure-based method for predicting protein interaction sites for DNA binding. DBSI was trained and validated on a data...