Julie C Mitchell
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Explore the profile of Julie C Mitchell including associated specialties, affiliations and a list of published articles.
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47
Citations
900
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Recent Articles
11.
Hu X, Zhang J, Kaundal R, Kataria R, Labbe J, Mitchell J, et al.
Hortic Res
. 2022 Feb;
PMID: 35184190
Arbuscular mycorrhizal symbiosis (AMS) is widespread mutualistic association between plants and fungi, which plays an essential role in nutrient exchange, enhancement in plant stress resistance, development of host, and ecosystem...
12.
Hameedi M, Prates E, Garvin M, Mathews I, Amos B, Demerdash O, et al.
bioRxiv
. 2021 Nov;
PMID: 34816264
In addition to its essential role in viral polyprotein processing, the SARS-CoV-2 3C-like (3CLpro) protease can cleave human immune signaling proteins, like NF-κB Essential Modulator (NEMO) and deregulate the host...
13.
Mishra S, Cooper C, Parks J, Mitchell J
J Phys Chem B
. 2021 Jun;
125(23):6058-6067.
PMID: 34077660
Protein-protein interactions play a key role in mediating numerous biological functions, with more than half the proteins in living organisms existing as either homo- or hetero-oligomeric assemblies. Protein subunits that...
14.
Aranha M, Jewel Y, Beckman R, Weiner L, Mitchell J, Parks J, et al.
J Immunol
. 2020 Sep;
205(7):1962-1977.
PMID: 32878910
The reliable prediction of the affinity of candidate peptides for the MHC is important for predicting their potential antigenicity and thus influences medical applications, such as decisions on their inclusion...
15.
Zhu X, Liu L, He J, Fang T, Xiong Y, Mitchell J
BMC Bioinformatics
. 2020 Jul;
21(1):289.
PMID: 32631222
Background: The interaction between proteins and nucleic acids plays pivotal roles in various biological processes such as transcription, translation, and gene regulation. Hot spots are a small set of residues...
16.
Aranha M, Spooner C, Demerdash O, Czejdo B, Smith J, Mitchell J
Biochim Biophys Acta Gen Subj
. 2020 Jan;
1864(4):129535.
PMID: 31954798
Selecting peptides that bind strongly to the major histocompatibility complex (MHC) for inclusion in a vaccine has therapeutic potential for infections and tumors. Machine learning models trained on sequence data...
17.
Bortnov V, Tonelli M, Lee W, Lin Z, Annis D, Demerdash O, et al.
Nat Commun
. 2019 Dec;
10(1):5612.
PMID: 31819058
Human myeloid-derived growth factor (hMYDGF) is a 142-residue protein with a C-terminal endoplasmic reticulum (ER) retention sequence (ERS). Extracellular MYDGF mediates cardiac repair in mice after anoxic injury. Although homologs...
18.
Demerdash O, Shrestha U, Petridis L, Smith J, Mitchell J, Ramanathan A
Front Mol Biosci
. 2019 Sep;
6:64.
PMID: 31475155
Intrinsically disordered proteins (IDPs) and proteins with intrinsically disordered regions (IDRs) play important roles in many aspects of normal cell physiology, such as signal transduction and transcription, as well as...
19.
Zhang H, Ericksen S, Lee C, Ananiev G, Wlodarchak N, Yu P, et al.
PLoS Comput Biol
. 2019 Aug;
15(8):e1006813.
PMID: 31381559
Prediction of compounds that are active against a desired biological target is a common step in drug discovery efforts. Virtual screening methods seek some active-enriched fraction of a library for...
20.
Liu L, Xiong Y, Gao H, Wei D, Mitchell J, Zhu X
Database (Oxford)
. 2018 Apr;
2018.
PMID: 29688380
http://zhulab.ahu.edu.cn/dbAMEPNI.