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Julie Bonne Kohler

Explore the profile of Julie Bonne Kohler including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 87
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Recent Articles
1.
Shi L, Derouiche A, Pandit S, Alazmi M, Ventroux M, Kohler J, et al.
Proc Natl Acad Sci U S A . 2024 Jun; 121(25):e2321890121. PMID: 38857388
In bacteria, attenuation of protein-tyrosine phosphorylation occurs during oxidative stress. The main described mechanism behind this effect is the HO-triggered conversion of bacterial phospho-tyrosines to protein-bound 3,4-dihydroxyphenylalanine. This disrupts the...
2.
Balasubramanian S, Kohler J, Jers C, Jensen P, Mijakovic I
Front Bioeng Biotechnol . 2024 Feb; 12:1348184. PMID: 38415189
The demand for alternative sources of food proteins is increasing due to the limitations and challenges associated with conventional food production. Advances in biotechnology have enabled the production of proteins...
3.
Sultan A, Jers C, Ganief T, Shi L, Senissar M, Kohler J, et al.
Front Microbiol . 2021 Apr; 12:657562. PMID: 33889145
Understanding phosphorylation-mediated regulation of metabolic enzymes, pathways, and cell phenotypes under metabolic shifts represents a major challenge. The kinases associated with most phosphorylation sites and the link between phosphorylation and...
4.
Jemaa M, Sime W, Abassi Y, Lasorsa V, Kohler J, Michaelis M, et al.
Int J Mol Sci . 2020 Sep; 21(18). PMID: 32948088
Drug resistance of childhood cancer neuroblastoma is a serious clinical problem. Patients with relapsed disease have a poor prognosis despite intense treatment. In the present study, we aimed to identify...
5.
Sime W, Jemaa M, Abassi Y, Lasorsa V, Kohler J, Hansson K, et al.
Int J Mol Sci . 2020 Sep; 21(18). PMID: 32911859
Neuroblastoma is a childhood solid tumour originating from undifferentiated neural progenitor cells of the sympathetic nervous system. Drug resistance of childhood cancer neuroblastoma is a serious clinical problem. In the...
6.
Kohler J, Jers C, Senissar M, Shi L, Derouiche A, Mijakovic I
FEBS Lett . 2020 Apr; 594(15):2339-2369. PMID: 32337704
Protein phosphorylation regulates a large variety of biological processes in all living cells. In pathogenic bacteria, the study of serine, threonine, and tyrosine (Ser/Thr/Tyr) phosphorylation has shed light on the...
7.
Sime W, Niu Q, Abassi Y, Masoumi K, Zarrizi R, Kohler J, et al.
Cell Death Dis . 2018 Apr; 9(5):458. PMID: 29686263
BRCA1-associated protein 1 (BAP1) is a nuclear deubiquitinating enzyme that is associated with multiprotein complexes that regulate key cellular pathways, including cell cycle, cellular differentiation, cell death, and the DNA...
8.
Kohler J, Tammsalu T, Jorgensen M, Steen N, Hay R, Thon G
Nat Commun . 2015 Nov; 6:8827. PMID: 26537787
In eukaryotes, the conjugation of proteins to the small ubiquitin-like modifier (SUMO) regulates numerous cellular functions. A proportion of SUMO conjugates are targeted for degradation by SUMO-targeted ubiquitin ligases (STUbLs)...
9.
Kohler J, Jorgensen M, Beinoraite G, Thorsen M, Thon G
PLoS One . 2013 Nov; 8(11):e80442. PMID: 24265825
In eukaryotes many players in the DNA-damage response (DDR) catalyze protein sumoylation or ubiquitylation. Emphasis has been placed on how these modifications orchestrate the sequential recruitment of repair factors to...