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Juliana M McElrath

Explore the profile of Juliana M McElrath including associated specialties, affiliations and a list of published articles. Areas
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Citations 5437
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Recent Articles
1.
deCamp A, Corcoran M, Fulp W, Willis J, Cottrell C, Bader D, et al.
NPJ Vaccines . 2024 Mar; 9(1):58. PMID: 38467663
Vaccine priming immunogens that activate germline precursors for broadly neutralizing antibodies (bnAbs) have promise for development of precision vaccines against major human pathogens. In a clinical trial of the eOD-GT8...
2.
deCamp A, Corcoran M, Fulp W, Willis J, Cottrell C, Bader D, et al.
medRxiv . 2023 Mar; PMID: 36993183
One-sentence Summary: Human genetic variation can modulate the strength of vaccine-induced broadly neutralizing antibody precursor B cell responses.
3.
Campion S, Brenna E, Thomson E, Fischer W, Ladell K, McLaren J, et al.
J Clin Invest . 2021 Dec; 131(23). PMID: 34850742
Naive and memory CD4+ T cells reactive with human immunodeficiency virus type 1 (HIV-1) are detectable in unexposed, unimmunized individuals. The contribution of preexisting CD4+ T cells to a primary...
4.
Hao Y, Hao S, Andersen-Nissen E, Mauck 3rd W, Zheng S, Butler A, et al.
Cell . 2021 Jun; 184(13):3573-3587.e29. PMID: 34062119
The simultaneous measurement of multiple modalities represents an exciting frontier for single-cell genomics and necessitates computational methods that can define cellular states based on multimodal data. Here, we introduce "weighted-nearest...
5.
Astronomo R, Santra S, Ballweber-Fleming L, Westerberg K, Mach L, Hensley-McBain T, et al.
EBioMedicine . 2016 Dec; 14:97-111. PMID: 27919754
HIV-1 infection occurs primarily through mucosal transmission. Application of biologically relevant mucosal models can advance understanding of the functional properties of antibodies that mediate HIV protection, thereby guiding antibody-based vaccine...
6.
Park H, Adamson L, Ha T, Mullen K, Hagen S, Nogueron A, et al.
J Immunol . 2013 Mar; 190(8):4103-15. PMID: 23509365
Prime-boost immunization with heterologous vaccines elicits potent cellular immunity. In this study, we assessed the influence of various TLR ligands on SIV Gag-specific T cell immunity and protection following prime-boost...
7.
Li F, McKenney D, Malhotra U, Crimi C, Nolin J, Corey L, et al.
Hum Vaccin . 2008 Apr; 4(2):115-21. PMID: 18382130
The cellular immune system is characterized by flexibility with respect to epitope recognition at the level of peptide binding to HLA molecules and HLA-peptide complexes to T-cell receptors (TCRs). For...
8.
Li F, Horton H, B Gilbert P, McElrath J, Corey L, Self S
Curr HIV Res . 2007 Feb; 5(1):97-107. PMID: 17266561
Much of the current effort in HIV-1 vaccine design is directed at achieving T-cell immunity that will result in enough immunological memory to contain HIV-1 infection after acquisition. However, antigenic...
9.
Li F, Malhotra U, B Gilbert P, Hawkins N, Duerr A, McElrath J, et al.
Vaccine . 2006 Aug; 24(47-48):6893-904. PMID: 16890329
Dozens of human immunodeficiency virus-type 1 (HIV-1) vaccine candidates specifically designed to elicit cytotoxic T-lymphocyte (CTL) responses have entered the pipeline of clinical trials. Evaluating the immunogenicity and potential efficacy...