Julia S Gauer
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Explore the profile of Julia S Gauer including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
176
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Recent Articles
1.
Gauer J, Ajanel A, Kaselampao L, Candir I, MacCannell A, Roberts L, et al.
Res Pract Thromb Haemost
. 2024 Sep;
8(6):102548.
PMID: 39309231
Background: Polyphenols have been shown to decrease oxidative stress and modulate glycemic response. Nevertheless, their effect on platelet bioenergetics and clot structure in diabetes and hyperglycemia is unknown. Objectives: To...
2.
Xu R, Tiede C, Calabrese A, Cheah L, Adams T, Gauer J, et al.
Blood Adv
. 2024 Jun;
8(15):3917-3928.
PMID: 38838227
Glycoprotein VI (GPVI) plays a key role in collagen-induced platelet aggregation. Affimers are engineered binding protein alternatives to antibodies. We screened and characterized GPVI-binding Affimers as novel tools to probe...
3.
Whyte C, Morrow G, Gauer J, Montague S, Nicolson P
Front Cardiovasc Med
. 2023 Sep;
10:1225243.
PMID: 37745127
The 2023 annual meeting of the British Society for Haemostasis and Thrombosis (BSHT) was held in Birmingham, United Kingdom. The theme of this year's meeting was novel therapeutics and emerging...
4.
Gauer J, Duval C, Xu R, Macrae F, McPherson H, Tiede C, et al.
J Thromb Haemost
. 2023 Jan;
21(3):667-681.
PMID: 36696196
Background: The glycoprotein VI (GPVI) signaling pathway was previously reported to direct procoagulant platelet activity through collagen binding. However, the impact of GPVI-fibrin interaction on procoagulant platelet development and how...
5.
Gauer J, Ajjan R, Ariens R
J Am Heart Assoc
. 2022 Oct;
11(20):e027071.
PMID: 36250653
Thromboinflammation has become a topic of key interest in cardiovascular disease and the prevention of diabetes complications because of the interplay between thrombosis and inflammation in diabetes. Specifically, the significant...
6.
Foster H, Wilson C, Gauer J, Xu R, Howard M, Manfield I, et al.
ACS Med Chem Lett
. 2022 Feb;
13(2):171-181.
PMID: 35178172
The GPVI platelet receptor was recently validated as a safe antiplatelet target for the treatment of thrombosis using several peptidic modulators. In contrast, few weakly potent small-molecule GPVI antagonists have...
7.
Xu R, Gauer J, Baker S, Slater A, Martin E, McPherson H, et al.
Arterioscler Thromb Vasc Biol
. 2021 Jan;
41(3):1092-1104.
PMID: 33472402
Objective: GPVI (glycoprotein VI) is a key molecular player in collagen-induced platelet signaling and aggregation. Recent evidence indicates that it also plays important role in platelet aggregation and thrombus growth...
8.
Gauer J, Riva N, Page E, Philippou H, Makris M, Gatt A, et al.
Res Pract Thromb Haemost
. 2020 Dec;
4(8):1269-1281.
PMID: 33313466
Background: Abnormal clot structure has been identified in patients with thrombotic disorders. Anticoagulant therapy offers clear benefits for thrombosis prevention and treatment by reducing blood clot formation and size; nevertheless,...
9.
Duval C, Profumo A, Aprile A, Salis A, Millo E, Damonte G, et al.
J Thromb Haemost
. 2020 Jan;
18(4):802-814.
PMID: 31889430
Background: Fibrin polymerization, following fibrinopeptides A and B (FpA, FpB) cleavage, relies on newly exposed α- and β-chains N-termini (GPR, GHR; A-, B-knobs, respectively) engaging preexistent a and b pockets...
10.
Kerimi A, Gauer J, Crabbe S, Cheah J, Lau J, Walsh R, et al.
Br J Nutr
. 2019 Jan;
121(7):782-792.
PMID: 30670104
Although polyphenols inhibit glucose absorption and transport in vitro, it is uncertain whether this activity is sufficient to attenuate glycaemic response in vivo. We examined this using orange juice, which...