Julia Mergner
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Explore the profile of Julia Mergner including associated specialties, affiliations and a list of published articles.
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25
Citations
611
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Recent Articles
1.
Koleci N, Wu Y, Wehner N, Rajak J, Mittapalli V, Mergner J, et al.
Cell Death Dis
. 2025 Mar;
16(1):165.
PMID: 40057493
Juvenile myelomonocytic leukemia (JMML) is caused by constitutively activated RAS signaling and characterized by increased proliferation and predominant myelomonocytic differentiation of hematopoietic cells. Using MxCre;Ptpn11 mice, which model human JMML,...
2.
Kardell O, Gronauer T, von Toerne C, Merl-Pham J, Konig A, Barth T, et al.
J Proteome Res
. 2025 Feb;
24(3):1017-1029.
PMID: 39918541
Advancing MS-based proteomics toward clinical applications evolves around developing standardized start-to-finish and fit-for-purpose workflows for clinical specimens. Steps along the method design involve the determination and optimization of several bioanalytical...
3.
Antoniolli M, Solovey M, Hildebrand J, Freyholdt T, Strobl C, Bararia D, et al.
Cell Death Differ
. 2025 Jan;
PMID: 39843653
The cell death receptor FAS and its ligand (FASLG) play crucial roles in the selection of B cells during the germinal center (GC) reaction. Failure to eliminate potentially harmful B...
4.
Rothfuss C, Baumann T, Donakonda S, Brauchle B, Marcinek A, Urban C, et al.
Blood
. 2025 Jan;
PMID: 39840945
Loss of anticancer NK cell function in AML patients is associated with fatal disease progression and remains poorly understood. Here, we demonstrate that AML-blasts isolated from patients rapidly inhibit NK...
5.
Janacek D, Kolb M, Schulz L, Mergner J, Kuster B, Glanc M, et al.
Dev Cell
. 2024 Oct;
59(24):3259-3271.e4.
PMID: 39413780
The phytohormone auxin is polarly transported in plants by PIN-FORMED (PIN) transporters and controls virtually all growth and developmental processes. Canonical PINs possess a long, largely disordered cytosolic loop. Auxin...
6.
Huang Y, Bergant V, Grass V, Emslander Q, Hamad M, Hubel P, et al.
Nat Commun
. 2024 Aug;
15(1):6778.
PMID: 39117661
Multiple omics analyzes of Vaccinia virus (VACV) infection have defined molecular characteristics of poxvirus biology. However, little is known about the monkeypox (mpox) virus (MPXV) in humans, which has a...
7.
Braun J, Hu Y, Jauch A, Gronauer T, Mergner J, Bach N, et al.
JACS Au
. 2024 May;
4(5):1833-1840.
PMID: 38818080
Neocarzilin (NCA) is a natural product exhibiting potent antimigratory as well as antiproliferative effects. While vesicle amine transport protein 1 (VAT-1) was previously shown to inhibit migration upon NCA binding,...
8.
Yoshida T, Mergner J, Yang Z, Liu J, Kuster B, Fernie A, et al.
Plant J
. 2024 Apr;
119(2):1112-1133.
PMID: 38613775
Phytohormones are essential signaling molecules regulating various processes in growth, development, and stress responses. Genetic and molecular studies, especially using Arabidopsis thaliana (Arabidopsis), have discovered many important players involved in...
9.
Graf A, Bassukas A, Xiao Y, Barbosa I, Mergner J, Grill P, et al.
Nat Plants
. 2024 Jan;
10(2):300-314.
PMID: 38278951
D6 PROTEIN KINASE (D6PK) is a polarly localized plasma-membrane-associated kinase from Arabidopsis thaliana that activates polarly distributed PIN-FORMED auxin transporters. D6PK moves rapidly to and from the plasma membrane, independent...
10.
Zhou L, Wang L, Chen X, Ge Z, Mergner J, Li X, et al.
Plant Cell
. 2023 Dec;
36(5):1673-1696.
PMID: 38142229
Autocrine signaling pathways regulated by RAPID ALKALINIZATION FACTORs (RALFs) control cell wall integrity during pollen tube germination and growth in Arabidopsis (Arabidopsis thaliana). To investigate the role of pollen-specific RALFs...