Julia Makhlin
Overview
Explore the profile of Julia Makhlin including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
130
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Recent Articles
1.
Ji J, Petropavlovskaia M, Khatchadourian A, Patapas J, Makhlin J, Rosenberg L, et al.
J Cell Mol Med
. 2019 Feb;
23(4):2890-2900.
PMID: 30710421
Both type 2 diabetes (T2D) and obesity are characterized by excessive hyperlipidaemia and subsequent lipid droplet (LD) accumulation in adipose tissue. To investigate whether LDs also accumulate in β-cells of...
2.
Assouline-Thomas B, Ellis D, Petropavlovskaia M, Makhlin J, Ding J, Rosenberg L
Differentiation
. 2015 Nov;
90(4-5):77-90.
PMID: 26558987
Regeneration of β-cells in diabetic patients is an important goal of diabetes research. Islet Neogenesis Associated Protein (INGAP) was discovered in the partially duct-obstructed hamster pancreas. Its bioactive fragment, pentadecapeptide...
3.
Petropavlovskaia M, Daoud J, Zhu J, Moosavi M, Ding J, Makhlin J, et al.
Am J Physiol Endocrinol Metab
. 2012 Aug;
303(7):E917-27.
PMID: 22850686
Islet neogenesis-associated protein (INGAP) was discovered in the partially duct-obstructed hamster pancreas as a factor inducing formation of new duct-associated islets. A bioactive portion of INGAP, INGAP(104-118) peptide (INGAP-P), has...
4.
Hanley S, Assouline-Thomas B, Makhlin J, Rosenberg L
J Endocrinol
. 2011 Sep;
211(3):231-9.
PMID: 21933872
Given the inherent therapeutic potential of the morphogenetic plasticity of adult human islets, the identification of factors controlling their cellular differentiation is of interest. The epidermal growth factor (EGF) family...
5.
Assouline-Thomas B, Pilotte A, Petropavlovskaia M, Makhlin J, Ding J, McLeod D, et al.
Protein Expr Purif
. 2009 Jul;
69(1):1-8.
PMID: 19635567
Islet Neogenesis Associated Protein (INGAP) is implicated in pancreatic islet neogenesis. INGAP peptide, a pentadecapeptide comprising amino acids 104-118, reverses diabetes in rodents and improves glucose homeostasis in patients with...
6.
Makhlin J, Kofman T, Borovok I, Kohler C, Engelmann S, Cohen G, et al.
J Bacteriol
. 2007 Jun;
189(16):5976-86.
PMID: 17557828
We identified a single open reading frame that is strongly similar to ArcR, a member of the Crp/Fnr family of bacterial transcriptional regulators, in all sequenced Staphylococcus aureus genomes. The...
7.
Petropavlovskaia M, Makhlin J, Sampalis J, Rosenberg L
J Endocrinol
. 2006 Oct;
191(1):65-81.
PMID: 17065390
Restoration of a functional beta-cell mass in a patient with diabetes may hold the key for curing the disease. In recent years, there has been increasing interest in the development...