Julia Kowal
Overview
Explore the profile of Julia Kowal including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
1492
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0
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Recent Articles
1.
Yu Q, Dehghani-Ghahnaviyeh S, Rasouli A, Sadurni A, Kowal J, Bang-Soerensen R, et al.
ACS Chem Biol
. 2024 Oct;
19(11):2304-2313.
PMID: 39445888
ABCG2 is a multidrug transporter that protects tissues from xenobiotics, affects drug pharmacokinetics, and contributes to multidrug resistance of cancer cells. Here, we present tetracyclic fumitremorgin C analog Ko143 derivatives,...
2.
Lampson B, Ramirez A, Baro M, He L, Hegde M, Koduri V, et al.
Cell
. 2024 Apr;
187(9):2209-2223.e16.
PMID: 38670073
Nuclear factor κB (NF-κB) plays roles in various diseases. Many inflammatory signals, such as circulating lipopolysaccharides (LPSs), activate NF-κB via specific receptors. Using whole-genome CRISPR-Cas9 screens of LPS-treated cells that...
3.
Liu H, Irobalieva R, Kowal J, Ni D, Nosol K, Bang-Sorensen R, et al.
Nat Commun
. 2023 Nov;
14(1):7296.
PMID: 37949847
BSEP (ABCB11) is an ATP-binding cassette transporter that is expressed in hepatocytes and extrudes bile salts into the canaliculi of the liver. BSEP dysfunction, caused by mutations or induced by...
4.
Ciuta A, Nosol K, Kowal J, Mukherjee S, Ramirez A, Stieger B, et al.
Nat Commun
. 2023 Sep;
14(1):5774.
PMID: 37723174
The organic anion transporting polypeptides OATP1B1 and OATP1B3 are membrane proteins that mediate uptake of drugs into the liver for subsequent conjugation and biliary excretion, a key step in drug...
5.
Micsinszki S, Tanel N, Kowal J, King G, Menna-Dack D, Chu A, et al.
Res Involv Engagem
. 2023 Jul;
9(1):54.
PMID: 37464394
Background: In 2019, our interdisciplinary team of researchers, family members, and youth co-designed four simulation training videos and accompanying facilitation resources to prepare youth, family members, trainees, and researchers to...
6.
Rasouli A, Yu Q, Dehghani-Ghahnaviyeh S, Wen P, Kowal J, Locher K, et al.
Proc Natl Acad Sci U S A
. 2022 Dec;
120(1):e2213437120.
PMID: 36580587
ABCG2 is an ATP-binding cassette (ABC) transporter that extrudes a wide range of xenobiotics and drugs from the cell and contributes to multidrug resistance in cancer cells. Following our recent...
7.
Ramirez A, de Capitani M, Pesciullesi G, Kowal J, Bloch J, Irobalieva R, et al.
Nat Commun
. 2022 Nov;
13(1):7296.
PMID: 36435935
Oligosaccharyltransferase (OST) is the central enzyme of N-linked protein glycosylation. It catalyzes the transfer of a pre-assembled glycan, GlcNAcManGlc, from a dolichyl-pyrophosphate donor to acceptor sites in secretory proteins in...
8.
Micsinszki S, Tanel N, Kowal J, King G, Menna-Dack D, Chu A, et al.
Res Involv Engagem
. 2022 Nov;
8(1):60.
PMID: 36352487
Background: Including youth with disabilities and their families as partners in childhood disability research is imperative but can be challenging to do in an authentic and meaningful way. Simulation allows...
9.
Neuhaus J, Wild R, Eyring J, Irobalieva R, Kowal J, Lin C, et al.
Glycobiology
. 2022 Jan;
31(12):1604-1615.
PMID: 34974622
The oligosaccharyltransferase (OST) is the central enzyme in the N-glycosylation pathway. It transfers a defined oligosaccharide from a lipid-linker onto the asparagine side chain of proteins. The yeast OST consists...
10.
Bloch J, Mukherjee S, Kowal J, Filippova E, Niederer M, Pardon E, et al.
Proc Natl Acad Sci U S A
. 2021 Nov;
118(47).
PMID: 34782475
With conformation-specific nanobodies being used for a wide range of structural, biochemical, and cell biological applications, there is a demand for antigen-binding fragments (Fabs) that specifically and tightly bind these...