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Julia Joung

Explore the profile of Julia Joung including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 11418
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Recent Articles
1.
Villiger L, Joung J, Koblan L, Weissman J, Abudayyeh O, Gootenberg J
Nat Rev Mol Cell Biol . 2024 May; 25(6):510. PMID: 38740926
No abstract available.
2.
Joung J, Ma S, Tay T, Geiger-Schuller K, Kirchgatterer P, Verdine V, et al.
Cell . 2024 May; 187(12):3161. PMID: 38697106
No abstract available.
3.
Villiger L, Joung J, Koblan L, Weissman J, Abudayyeh O, Gootenberg J
Nat Rev Mol Cell Biol . 2024 Feb; 25(6):464-487. PMID: 38308006
Our ability to edit genomes lags behind our capacity to sequence them, but the growing understanding of CRISPR biology and its application to genome, epigenome and transcriptome engineering is narrowing...
4.
Tzouanas C, Sherman M, Shay J, Rubin A, Mead B, Dao T, et al.
bioRxiv . 2023 Dec; PMID: 38077056
Under chronic stress, cells must balance competing demands between cellular survival and tissue function. In metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD/NASH), hepatocytes cooperate with structural and immune cells...
5.
Dolan M, Therrien M, Jereb S, Kamath T, Gazestani V, Atkeson T, et al.
Nat Immunol . 2023 Jul; 24(8):1382-1390. PMID: 37500887
Microglia, the macrophages of the brain parenchyma, are key players in neurodegenerative diseases such as Alzheimer's disease. These cells adopt distinct transcriptional subtypes known as states. Understanding state function, especially...
6.
Joung J, Ma S, Tay T, Geiger-Schuller K, Kirchgatterer P, Verdine V, et al.
Cell . 2023 Jan; 186(1):209-229.e26. PMID: 36608654
Transcription factors (TFs) regulate gene programs, thereby controlling diverse cellular processes and cell states. To comprehensively understand TFs and the programs they control, we created a barcoded library of all...
7.
Patchsung M, Homchan A, Aphicho K, Suraritdechachai S, Wanitchanon T, Pattama A, et al.
CRISPR J . 2022 Nov; 6(2):99-115. PMID: 36367987
Point-of-care (POC) nucleic acid detection technologies are poised to aid gold-standard technologies in controlling the COVID-19 pandemic, yet shortcomings in the capability to perform critically needed complex detection-such as multiplexed...
8.
Larson R, Kann M, Bailey S, Haradhvala N, Montero Llopis P, Bouffard A, et al.
Nature . 2022 Apr; 604(7906):563-570. PMID: 35418687
Chimeric antigen receptor (CAR) therapy has had a transformative effect on the treatment of haematologic malignancies, but it has shown limited efficacy against solid tumours. Solid tumours may have cell-intrinsic...
9.
Joung J, Kirchgatterer P, Singh A, Cho J, Nety S, Larson R, et al.
Nat Commun . 2022 Mar; 13(1):1606. PMID: 35338135
The cellular processes that govern tumor resistance to immunotherapy remain poorly understood. To gain insight into these processes, here we perform a genome-scale CRISPR activation screen for genes that enable...
10.
Nie M, Du L, Ren W, Joung J, Ye X, Shi X, et al.
Cell Death Dis . 2021 Apr; 12(5):419. PMID: 33911074
Diffuse large B-cell lymphoma (DLBCL) is the most common type of aggressive lymphoid malignancy and a highly heterogeneous disease. In this study, we performed whole-genome and transcriptome sequencing, and a...