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Julia Hinterdobler

Explore the profile of Julia Hinterdobler including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 194
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Recent Articles
1.
Riera-Tur I, Hinterdobler J, Maaske A, Sadewasser A, Schell M, Sekar J, et al.
Nucleic Acid Ther . 2024 Jul; 34(5):257-271. PMID: 39018509
Early characterization of the immunostimulatory potential of therapeutic antisense oligonucleotides (ASOs) is crucial. At present, little is known about the toll-like receptor 9 (TLR9)-mediated immunostimulatory potential of third-generation locked nucleic...
2.
Sharifi M, Wierer M, Dang T, Milic J, Moggio A, Sachs N, et al.
Circ Res . 2023 Sep; 133(8):674-686. PMID: 37675562
Background: The locus was genome-wide significantly associated with coronary artery disease. Lack of the ECM (extracellular matrix) protease ADAMTS-7 (A disintegrin and metalloproteinase-7) was shown to reduce atherosclerotic plaque formation....
3.
Meyer-Lindemann U, Mauersberger C, Schmidt A, Moggio A, Hinterdobler J, Li X, et al.
Front Immunol . 2022 Jul; 13:898690. PMID: 35860249
Background: Inflammation strongly contributes to atherosclerosis initiation and progression. Consequently, recent clinical trials pharmacologically targeted vascular inflammation to decrease the incidence of atherosclerosis-related complications. Colchicine, a microtubule inhibitor with anti-inflammatory...
4.
Mauersberger C, Hinterdobler J, Schunkert H, Kessler T, Sager H
Front Cardiovasc Med . 2022 Jan; 8:813984. PMID: 35087886
Atherosclerosis is the leading cause of death worldwide and leukocyte recruitment is a key element of this phenomenon, thus allowing immune cells to enter the arterial wall. There, in concert...
5.
Hettwer J, Hinterdobler J, Miritsch B, Deutsch M, Li X, Mauersberger C, et al.
Cardiovasc Res . 2021 Oct; 118(13):2778-2791. PMID: 34718444
Aims: Targeting vascular inflammation represents a novel therapeutic approach to reduce complications of atherosclerosis. Neutralizing the pro-inflammatory cytokine interleukin-1β (IL-1β) using canakinumab, a monoclonal antibody, reduces the incidence of cardiovascular...
6.
Aliluev A, Tritschler S, Sterr M, Oppenlander L, Hinterdobler J, Greisle T, et al.
Nat Metab . 2021 Sep; 3(9):1202-1216. PMID: 34552271
Excess nutrient uptake and altered hormone secretion in the gut contribute to a systemic energy imbalance, which causes obesity and an increased risk of type 2 diabetes and colorectal cancer....
7.
Hinterdobler J, Schunkert H, Kessler T, Sager H
Antioxid Redox Signal . 2021 Jul; 35(18):1531-1550. PMID: 34293932
Atherosclerosis and its complications, such as acute coronary syndromes, are the leading causes of death worldwide. A wide range of inflammatory processes substantially contribute to the initiation and progression of...
8.
Hinterdobler J, Schott S, Jin H, Meesmann A, Steinsiek A, Zimmermann A, et al.
Eur Heart J . 2021 Jul; 42(39):4077-4088. PMID: 34279021
Aims: Mental stress substantially contributes to the initiation and progression of human disease, including cardiovascular conditions. We aim to investigate the underlying mechanisms of these contributions since they remain largely...
9.
Winkler M, Muller P, Sharifi A, Wobst J, Winter H, Mokry M, et al.
Basic Res Cardiol . 2020 Nov; 115(6):67. PMID: 33185739
A missense variant of the sushi, von Willebrand factor type A, EGF and pentraxin domain containing protein 1 (SVEP1) is genome-wide significantly associated with coronary artery disease. The mechanisms how...