Juho Vaananen
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Explore the profile of Juho Vaananen including associated specialties, affiliations and a list of published articles.
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10
Citations
95
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Recent Articles
1.
Pehkonen H, Filippou A, Vaananen J, Lindfors I, Vanttinen M, Ianevski P, et al.
Mol Oncol
. 2024 Jan;
18(3):662-676.
PMID: 38264964
PTPRF interacting protein alpha 1 (PPFIA1) encodes for liprin-α1, a member of the leukocyte common antigen-related protein tyrosine phosphatase (LAR-RPTPs)-interacting protein family. Liprin-α1 localizes to adhesive and invasive structures in...
2.
Olkinuora A, Nieminen T, Douglas S, Kauppinen A, Kontro M, Vaananen J, et al.
Leukemia
. 2023 Sep;
37(11):2301-2305.
PMID: 37696923
No abstract available.
3.
Gigliotta A, Trontti K, Vaananen J, Hovatta I
Front Genet
. 2023 Jun;
14:1173376.
PMID: 37260777
Anxiety is an evolutionarily conserved response that is essential for survival. Pathological anxiety, however, is a maladaptive response to nonthreatening situations and greatly affects quality of life. The recent COVID-19...
4.
Kurtzeborn K, Kwon H, Iaroshenko V, Faisal I, Ambroz M, Jin X, et al.
BMC Biol
. 2022 May;
20(1):112.
PMID: 35550069
Background: MAPK/ERK signaling is a well-known mediator of extracellular stimuli controlling intracellular responses to growth factors and mechanical cues. The critical requirement of MAPK/ERK signaling for embryonic stem cell maintenance...
5.
Viitasalo S, Karhemo P, Vaananen J, Ilmarinen T, Lilja M, Katainen R, et al.
Oral Oncol
. 2021 Dec;
124:105663.
PMID: 34915258
We explored somatic mutations in dysplastic sinonasal inverted papilloma (SNIP), SNIP with concomitant sinonasal squamous cell carcinoma (SNSCC), and SNSCC without preceding SNIP. Ten SNIP and SNSCC samples were analyzed...
6.
Munne P, Martikainen L, Raty I, Bertula K, Nonappa , Ruuska J, et al.
Nat Commun
. 2021 Nov;
12(1):6967.
PMID: 34845227
Breast cancer is now globally the most frequent cancer and leading cause of women's death. Two thirds of breast cancers express the luminal estrogen receptor-positive (ERα + ) phenotype that...
7.
Filippou A, Pehkonen H, Karhemo P, Vaananen J, Nieminen A, Klefstrom J, et al.
Cancers (Basel)
. 2021 Apr;
13(5).
PMID: 33803266
Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group of tumors that derive from the mucosal epithelium of the upper aerodigestive tract and present high mortality rate. Lack...
8.
Wahbi W, Naakka E, Tuomainen K, Suleymanova I, Arpalahti A, Miinalainen I, et al.
Exp Cell Res
. 2020 Feb;
389(1):111885.
PMID: 32017929
The interaction between squamous cell carcinoma (SCC) cells and the tumor microenvironment (TME) plays a major role in cancer progression. Therefore, understanding the TME is essential for the development of...
9.
Trontti K, Vaananen J, Sipila T, Greco D, Hovatta I
RNA
. 2018 Feb;
24(5):643-655.
PMID: 29445025
Diversity in the structure and expression of microRNAs, important regulators of gene expression, arises from SNPs, duplications followed by divergence, production of isomiRs, and RNA editing. Inbred mouse strains and...
10.
Mattila J, Havula E, Suominen E, Teesalu M, Surakka I, Hynynen R, et al.
Cell Rep
. 2015 Oct;
13(2):350-64.
PMID: 26440885
The ChREBP/Mondo-Mlx transcription factors are activated by sugars and are essential for sugar tolerance. They promote the conversion of sugars to lipids, but beyond this, their physiological roles are insufficiently...