Piia-Riitta Karhemo
Overview
Explore the profile of Piia-Riitta Karhemo including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
11
Citations
117
Followers
0
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Pehkonen H, Filippou A, Vaananen J, Lindfors I, Vanttinen M, Ianevski P, et al.
Mol Oncol
. 2024 Jan;
18(3):662-676.
PMID: 38264964
PTPRF interacting protein alpha 1 (PPFIA1) encodes for liprin-α1, a member of the leukocyte common antigen-related protein tyrosine phosphatase (LAR-RPTPs)-interacting protein family. Liprin-α1 localizes to adhesive and invasive structures in...
2.
Sjoblom A, Pehkonen H, Jouhi L, Monni O, Randen-Brady R, Karhemo P, et al.
Head Neck Pathol
. 2023 Jun;
17(3):647-657.
PMID: 37335526
Background: Liprin-α1 is a scaffold protein involved in cell adhesion, motility, and invasion in malignancies. Liprin-α1 inhibits the expression of metastatic suppressor CD82 in cancers such as oral carcinoma, and...
3.
Viitasalo S, Karhemo P, Vaananen J, Ilmarinen T, Lilja M, Katainen R, et al.
Oral Oncol
. 2021 Dec;
124:105663.
PMID: 34915258
We explored somatic mutations in dysplastic sinonasal inverted papilloma (SNIP), SNIP with concomitant sinonasal squamous cell carcinoma (SNSCC), and SNSCC without preceding SNIP. Ten SNIP and SNSCC samples were analyzed...
4.
Filippou A, Pehkonen H, Karhemo P, Vaananen J, Nieminen A, Klefstrom J, et al.
Cancers (Basel)
. 2021 Apr;
13(5).
PMID: 33803266
Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group of tumors that derive from the mucosal epithelium of the upper aerodigestive tract and present high mortality rate. Lack...
5.
Tuomainen K, Al-Samadi A, Potdar S, Turunen L, Turunen M, Karhemo P, et al.
Cancers (Basel)
. 2020 Jan;
12(1).
PMID: 31905951
In vitro cancer drug testing carries a low predictive value. We developed the human leiomyoma-derived matrix "Myogel" to better mimic the human tumor microenvironment (TME). We hypothesized that Myogel could...
6.
Lepikhova T, Karhemo P, Louhimo R, Yadav B, Murumagi A, Kulesskiy E, et al.
Mol Cancer Ther
. 2018 Jul;
17(9):2060-2071.
PMID: 29970484
There is an unmet need for effective targeted therapies for patients with advanced head and neck squamous cell carcinoma (HNSCC). We correlated gene expression, gene copy numbers, and point mutations...
7.
Salmenpera P, Karhemo P, Rasanen K, Laakkonen P, Vaheri A
Exp Cell Res
. 2016 May;
345(1):17-24.
PMID: 27177832
Stromal fibroblasts have an important role in regulating tumor progression. Normal and quiescent fibroblasts have been shown to restrict and control cancer cell growth, while cancer-associated, i. e. activated fibroblasts...
8.
Pehkonen H, von Nandelstadh P, Karhemo P, Lepikhova T, Grenman R, Lehti K, et al.
Sci Rep
. 2016 Apr;
6:24486.
PMID: 27075696
PPFIA1 is located at the 11q13 region, which is one of the most commonly amplified regions in several epithelial cancers including head and neck squamous cell carcinoma and breast carcinoma....
9.
Karhemo P, Hyvonen M, Laakkonen P
Front Pharmacol
. 2012 Nov;
3:192.
PMID: 23162466
Oncoproteomics aims to the discovery of molecular markers, drug targets, and pathways by studying cancer specific protein expression, localization, modification, and interaction. Cell surface proteins play a central role in...
10.
Karhemo P, Ravela S, Laakso M, Ritamo I, Tatti O, Makinen S, et al.
J Proteomics
. 2012 Jul;
77:87-100.
PMID: 22813880
Details of metastasis, the deadliest aspect of cancer, are unclear. Cell surface proteins play central roles in adhesive contacts between the tumor cell and the stroma during metastasis. We optimized...