Juha Kuja-Panula
Overview
Explore the profile of Juha Kuja-Panula including associated specialties, affiliations and a list of published articles.
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21
Citations
747
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Recent Articles
1.
Kulesskaya N, Mugantseva E, Minkeviciene R, Acosta N, Rouhiainen A, Kuja-Panula J, et al.
Front Cell Dev Biol
. 2022 May;
10:865275.
PMID: 35547817
Protamine is an arginine-rich peptide that replaces histones in the DNA-protein complex during spermatogenesis. Protamine is clinically used in cardiopulmonary bypass surgery to neutralize the effects of heparin that is...
2.
Rouhiainen A, Nykanen N, Kuja-Panula J, Vanttola P, Huttunen H, Rauvala H
Medicines (Basel)
. 2018 Aug;
5(3).
PMID: 30061484
Heparin and heparin-related sulphated carbohydrates inhibit ligand binding of the receptor for advanced glycation end products (RAGE). Here, we have studied the ability of heparin to inhibit homophilic interactions of...
3.
Bishop H, Cobb M, Kirmiz M, Parajuli L, Mandikian D, Philp A, et al.
Front Mol Neurosci
. 2018 Feb;
11:1.
PMID: 29403353
Voltage-gated K (Kv) channels play important roles in regulating neuronal excitability. Kv channels comprise four principal α subunits, and transmembrane and/or cytoplasmic auxiliary subunits that modify diverse aspects of channel...
4.
Rauvala H, Paveliev M, Kuja-Panula J, Kulesskaya N
Neural Regen Res
. 2017 Jun;
12(5):687-691.
PMID: 28616017
The current dogma in neural regeneration research implies that chondroitin sulfate proteoglycans (CSPGs) inhibit plasticity and regeneration in the adult central nervous system (CNS). We argue that the role of...
5.
Li Z, Khan M, Kuja-Panula J, Wang H, Chen Y, Guo D, et al.
Brain Behav Immun
. 2017 Jan;
62:110-123.
PMID: 28119027
The immune function of AMIGO2 is currently unknown. Here, we revealed novel roles of AMIGO2 in modulating T-cell functions and EAE using Amigo2-knockout (AMG2KO) mice. Amigo2 was abundantly expressed by...
6.
Paveliev M, Fenrich K, Kislin M, Kuja-Panula J, Kulesskiy E, Varjosalo M, et al.
Sci Rep
. 2016 Sep;
6:33916.
PMID: 27671118
Chondroitin sulfate (CS) glycosaminoglycans inhibit regeneration in the adult central nervous system (CNS). We report here that HB-GAM (heparin-binding growth-associated molecule; also known as pleiotrophin), a CS-binding protein expressed at...
7.
Rouhiainen A, Zhao X, Vanttola P, Qian K, Kulesskiy E, Kuja-Panula J, et al.
Sci Rep
. 2016 Sep;
6:32960.
PMID: 27608812
HMGB4 is a new member in the family of HMGB proteins that has been characterized in sperm cells, but little is known about its functions in somatic cells. Here we...
8.
Peltola M, Kuja-Panula J, Liuhanen J, Voikar V, Piepponen P, Hiekkalinna T, et al.
Schizophr Bull
. 2015 Aug;
42(1):191-201.
PMID: 26240432
The enormous variability in electrical properties of neurons is largely affected by a multitude of potassium channel subunits. Kv2.1 is a widely expressed voltage-dependent potassium channel and an important regulator...
9.
Zhao X, Kuja-Panula J, Sundvik M, Chen Y, Aho V, Peltola M, et al.
J Biol Chem
. 2014 Jun;
289(29):19958-75.
PMID: 24904058
The Amigo protein family consists of three transmembrane proteins characterized by six leucine-rich repeat domains and one immunoglobulin-like domain in their extracellular moieties. Previous in vitro studies have suggested a...
10.
Rouhiainen A, Kuja-Panula J, Tumova S, Rauvala H
Methods Mol Biol
. 2013 Jan;
963:239-63.
PMID: 23296615
RAGE (receptor for advanced glycation end products) is a multi-ligand receptor that belongs to the immunoglobulin superfamily of transmembrane proteins. RAGE binds AGEs (advanced glycation end products), HMGB1 (high-mobility group...