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Juergen Hescheler

Explore the profile of Juergen Hescheler including associated specialties, affiliations and a list of published articles. Areas
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Articles 52
Citations 1545
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Recent Articles
11.
Rubach M, Adelmann R, Haustein M, Drey F, Pfannkuche K, Xiao B, et al.
Stem Cells Dev . 2013 Nov; 23(6):643-53. PMID: 24219308
Induced pluripotent stem cell-derived cardiomyocytes (iPS-CMs) might become therapeutically relevant to regenerate myocardial damage. Purified iPS-CMs exhibit poor functional integration into myocardial tissue. The aim of this study was to...
12.
Hoebaus J, Heher P, Gottschamel T, Scheinast M, Auner H, Walder D, et al.
Cells Tissues Organs . 2013 Jan; 197(4):249-68. PMID: 23343517
Compelling evidence for the existence of somatic stem cells in the heart of different mammalian species has been provided by numerous groups; however, so far it has not been possible...
13.
Bassam R, Digel I, Hescheler J, Artmann A, Artmann G
BMC Biophys . 2013 Jan; 6:1. PMID: 23289636
Unlabelled: Background And Objective: Regulating protein function in the cell by small molecules, provide a rapid, reversible and tunable tool of metabolic control. However, due to its complexity the issue...
14.
Klaric M, Winkler J, Vojnits K, Meganathan K, Jagtap S, Ensenat-Waser R, et al.
Front Biosci (Schol Ed) . 2013 Jan; 5(1):118-33. PMID: 23277040
The present review assesses the current status of in vitro tests based on human pluripotent stem cell-derived toxicologically relevant target cells. The majority of the evaluated test systems are in...
15.
Dehghani L, Farokhpour M, Karbalaie K, Nematollahi M, Tanhaie S, Hayati-Rodbari N, et al.
Tissue Cell . 2012 Nov; 45(2):101-6. PMID: 23141520
Embryonic stem cells (ESCs) have various uses in drug toxicity, as they can be easily differentiated in vitro. However, one of the major obstacles in the assessment of these differentiated...
16.
Bassam R, Hescheler J, Temiz-Artmann A, Artmann G, Digel I
BMC Biophys . 2012 Aug; 5:16. PMID: 22929146
Background: Minor changes in protein structure induced by small organic and inorganic molecules can result in significant metabolic effects. The effects can be even more profound if the molecular players...
17.
Halbach M, Krausgrill B, Hannes T, Wiedey M, Peinkofer G, Baumgartner S, et al.
J Mol Cell Cardiol . 2012 Jun; 53(3):401-8. PMID: 22728218
Electrophysiological maturation and integration of transplanted cardiomyocytes are essential to enhance safety and efficiency of cell replacement therapy. Yet, little is known about these important processes. The aim of our...
18.
Pillekamp F, Haustein M, Khalil M, Emmelheinz M, Nazzal R, Adelmann R, et al.
Stem Cells Dev . 2012 Jan; 21(12):2111-21. PMID: 22268955
Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) provide the unique opportunity to study the very early development of the human heart. The aim of this study was to investigate the effect...
19.
Wagh V, Jagtap S, Meganathan K, Potta S, Winkler J, Hescheler J, et al.
Front Biosci (Elite Ed) . 2011 Dec; 4(1):156-68. PMID: 22201861
Chemopreventive agents are derived from edible plants and from ancient time is a part of daily intake for many humans and animals. There are several lines of compelling evidence from...
20.
Fatima A, Xu G, Shao K, Papadopoulos S, Lehmann M, Arnaiz-Cot J, et al.
Cell Physiol Biochem . 2011 Dec; 28(4):579-92. PMID: 22178870
Background/aims: Induced pluripotent stem (iPS) cells generated from accessible adult cells of patients with genetic diseases open unprecedented opportunities for exploring the pathophysiology of human diseases in vitro. Catecholaminergic polymorphic...