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Judy K Shigenaga

Explore the profile of Judy K Shigenaga including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 1580
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Recent Articles
1.
Kuffer A, Straus L, Prather A, Inslicht S, Richards A, Shigenaga J, et al.
Psychoneuroendocrinology . 2018 Dec; 102:114-120. PMID: 30544002
Background: Posttraumatic stress disorder (PTSD) is associated with disturbed sleep and elevated levels of pro-inflammatory cytokines, including interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α). Studies in animals and healthy humans...
2.
ODonovan A, Chao L, Paulson J, Samuelson K, Shigenaga J, Grunfeld C, et al.
Psychoneuroendocrinology . 2014 Dec; 51:557-66. PMID: 25465168
Background: Inflammation may reduce hippocampal volume by blocking neurogenesis and promoting neurodegeneration. Posttraumatic stress disorder (PTSD) has been linked with both elevated inflammation and reduced hippocampal volume. However, few studies...
3.
Feingold K, Moser A, Shigenaga J, Grunfeld C
J Lipid Res . 2014 Oct; 55(12):2501-8. PMID: 25320346
Many of the beneficial and adverse effects of niacin are mediated via a G protein receptor, G protein-coupled receptor 109A/hydroxycarboxylic acid 2 receptor (GPR109A/HCA2), which is highly expressed in adipose...
4.
Feingold K, Shigenaga J, Kazemi M, McDonald C, Patzek S, Cross A, et al.
J Leukoc Biol . 2012 Jul; 92(4):829-39. PMID: 22753953
LPS treatment of macrophages induces TG accumulation, which is accentuated by TG-rich lipoproteins or FFA. We defined pathways altered during macrophage activation that contribute to TG accumulation. Glucose uptake increased...
5.
Feingold K, Shigenaga J, Cross A, Moser A, Grunfeld C
Biochem Biophys Res Commun . 2012 Apr; 421(3):612-5. PMID: 22538368
Angiopoietin like protein 4 (ANGPTL4) inhibits lipoprotein lipase (LPL) activity. Previous studies have shown that Toll-like Receptor (TLR) activation increases serum levels of ANGPTL4 and expression of ANGPTL4 in liver,...
6.
Feingold K, Grunfeld C, Heuer J, Gupta A, Cramer M, Zhang T, et al.
Endocrinology . 2012 Apr; 153(6):2689-700. PMID: 22474187
The acute phase response (APR) produces marked alterations in lipid and carbohydrate metabolism including decreasing plasma ketone levels. Fibroblast growth factor 21 (FGF21) is a recently discovered hormone that regulates...
7.
Feingold K, Moser A, Shigenaga J, Grunfeld C
Inflamm Res . 2011 Jul; 60(10):991-5. PMID: 21751047
Objective And Design: The aim of this study was to examine the expression of G protein-coupled receptor 81 (GPR81) in mouse adipose tissue in response to inflammatory stimuli. GPR81 is...
8.
Feingold K, Moser A, Shigenaga J, Grunfeld C
Innate Immun . 2011 Apr; 18(2):231-40. PMID: 21450790
Inhibition of adipocyte triglyceride biosynthesis is required for fatty acid mobilization during inflammation. Triglyceride biosynthesis requires glycerol 3-phosphate and phosphoenolpyruvate carboxykinase (PEPCK) plays a key role. We demonstrate that LPS,...
9.
Rooney T, Scherzer R, Shigenaga J, Graf J, Imboden J, Grunfeld C
Rheumatology (Oxford) . 2011 Mar; 50(8):1458-65. PMID: 21441551
Objective: Patients with RA have systemic inflammation and increased risk of cardiovascular (CV) events, including thrombosis. Levels of fibrinogen, a pro-thrombotic protein with predictive value for CV disease (CVD), are...
10.
Feingold K, Shigenaga J, Patzek S, Chui L, Moser A, Grunfeld C
Innate Immun . 2010 Jan; 17(2):174-82. PMID: 20100709
Carbohydrate response element binding protein (ChREBP) is a recently discovered transcription factor whose levels and activity are increased by glucose leading to the activation of target genes, which include acetyl-CoA...