Juan Miguel Redondo
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Explore the profile of Juan Miguel Redondo including associated specialties, affiliations and a list of published articles.
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81
Citations
2439
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Recent Articles
1.
Soudant J, Gonzalez-Blazquez R, Merino A, Ballesteros-Martinez C, Rodrigues-Diez R, Moreno-Carriles R, et al.
Clin Investig Arterioscler
. 2025 Mar;
:500769.
PMID: 40023687
Introduction: Inflammation is a major determinant of abdominal aortic aneurysms (AAA). Interferon stimulated gene 15 (ISG15) has a role in vascular remodelling in AAA. This study investigates the mechanisms whereby...
2.
Gomez-Del Arco P, Isern J, Jimenez-Carretero D, Lopez-Maderuelo D, Pineiro-Sabaris R, El Abdellaoui-Soussi F, et al.
Nat Commun
. 2024 Oct;
15(1):8602.
PMID: 39366945
Extensive genetic studies have elucidated cardiomyocyte differentiation and associated gene networks using single-cell RNA-seq, yet the intricate transcriptional mechanisms governing cardiac conduction system (CCS) development and working cardiomyocyte differentiation remain...
3.
Versican accumulation drives Nos2 induction and aortic disease in Marfan syndrome via Akt activation
Ruiz-Rodriguez M, Oller J, Martinez-Martinez S, Alarcon-Ruiz I, Toral M, Sun Y, et al.
EMBO Mol Med
. 2024 Jan;
16(1):132-157.
PMID: 38177536
Thoracic aortic aneurysm and dissection (TAAD) is a life-threatening condition associated with Marfan syndrome (MFS), a disease caused by fibrillin-1 gene mutations. While various conditions causing TAAD exhibit aortic accumulation...
4.
El Abdellaoui-Soussi F, Yunes-Leites P, Lopez-Maderuelo D, Garcia-Marques F, Vazquez J, Redondo J, et al.
Int J Mol Sci
. 2022 Sep;
23(17).
PMID: 36076959
The sarcomere regulates striated muscle contraction. This structure is composed of several myofibril proteins, isoforms of which are encoded by genes specific to either the heart or skeletal muscle. The...
5.
Ahmed S, Kurusamy S, David E, Khan K, Kalyanakrishnan K, Ian-Gobo M, et al.
Sci Rep
. 2022 Aug;
12(1):14730.
PMID: 36042288
Angiogenesis is a multi-factorial physiological process deregulated in human diseases characterised by excessive or insufficient blood vessel formation. Emerging evidence highlights a novel role for microRNAs as regulators of angiogenesis....
6.
Oller J, Gabande-Rodriguez E, Roldan-Montero R, Ruiz-Rodriguez M, Redondo J, Martin-Ventura J, et al.
Arterioscler Thromb Vasc Biol
. 2022 Feb;
42(4):462-469.
PMID: 35196876
Background: The goal of this study was to determine whether boosting mitochondrial respiration prevents the development of fatal aortic ruptures triggered by atherosclerosis and hypertension. Methods: Ang-II (angiotensin-II) was infused...
7.
Garcia-Izquierdo E, Mingo-Santos S, Olivo-Rodriguez C, Monivas-Palomero V, Rivas-Lasarte M, Martin-Lopez C, et al.
Int J Cardiol
. 2022 Jan;
352:125-130.
PMID: 35092759
Background: Increased collagen cross-linking (CCL) has been described in hypertensive cardiomyopathy by means of reduced serum ratio of serum carboxyterminal telopeptide of collagen type I (CITP) to matrix metalloproteinase-1 (MMP1)....
8.
Gonzalez-Amor M, Garcia-Redondo A, Jorge I, Zalba G, Becares M, Ruiz-Rodriguez M, et al.
Cardiovasc Res
. 2021 Oct;
118(16):3250-3268.
PMID: 34672341
Aims: Interferon-stimulated gene 15 (ISG15) encodes a ubiquitin-like protein that induces a reversible post-translational modification (ISGylation) and can also be secreted as a free form. ISG15 plays an essential role...
9.
Toral M, de la Fuente-Alonso A, Campanero M, Redondo J
Br J Pharmacol
. 2021 Oct;
179(7):1287-1303.
PMID: 34599830
Recent studies have shown that NO is a central mediator in diseases associated with thoracic aortic aneurysm, such as Marfan syndrome. The progressive dilation of the aorta in thoracic aortic...
10.
Sreenivasan K, Rodriguez-delaRosa A, Kim J, Mesquita D, Segales J, Gomez-Del Arco P, et al.
Stem Cell Reports
. 2021 Aug;
16(9):2089-2098.
PMID: 34450038
Regeneration of skeletal muscle requires resident stem cells called satellite cells. Here, we report that the chromatin remodeler CHD4, a member of the nucleosome remodeling and deacetylase (NuRD) repressive complex,...