Juan Hidalgo
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Explore the profile of Juan Hidalgo including associated specialties, affiliations and a list of published articles.
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111
Citations
4008
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Recent Articles
11.
Laitano O, Robinson G, Garcia C, Mattingly A, Sheikh L, Murray K, et al.
Shock
. 2020 Aug;
55(5):676-685.
PMID: 32826815
Interleukin-6 (IL-6) is a major cytokine released by skeletal muscle. Although IL-6 plays complex but well-known roles in host defense, the specific contribution of skeletal muscle IL-6 to innate immunity...
12.
Escrig A, Molinero A, Mendez B, Giralt M, Comes G, Sanchis P, et al.
Cells
. 2020 Jul;
9(7).
PMID: 32630818
Alzheimer's disease (AD) is a neurodegenerative disorder that causes the most prevalent dementia in the elderly people. Obesity and insulin resistance, which may cause major health problems , are risk...
13.
Chowdhury S, Schulz L, Palmisano B, Singh P, Berger J, Yadav V, et al.
J Clin Invest
. 2020 Feb;
130(6):2888-2902.
PMID: 32078586
Given the numerous health benefits of exercise, understanding how exercise capacity is regulated is a question of paramount importance. Circulating interleukin 6 (IL-6) levels surge during exercise and IL-6 favors...
14.
Sanchis P, Fernandez-Gayol O, Comes G, Escrig A, Giralt M, Palmiter R, et al.
Cells
. 2020 Feb;
9(2).
PMID: 32023844
Background: Interleukin-6 (IL-6) is a pleiotropic and multifunctional cytokine that plays a critical role in induction of experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis (MS). Although EAE...
15.
Han M, White A, Perry R, Camporez J, Hidalgo J, Shulman G, et al.
Proc Natl Acad Sci U S A
. 2020 Jan;
117(6):2751-2760.
PMID: 31980524
Obesity is associated with a chronic state of low-grade inflammation and progressive tissue infiltration by immune cells and increased expression of inflammatory cytokines. It is established that interleukin 6 (IL6)...
16.
Sanchis P, Fernandez-Gayol O, Vizueta J, Comes G, Canal C, Escrig A, et al.
Glia
. 2019 Dec;
68(5):999-1016.
PMID: 31799746
Traumatic brain injury (TBI) is a major health problem with high rates of mortality and morbidity worldwide. The response of the brain to TBI is orchestrated by a number of...
17.
Wilkinson A, Chang K, Kuns R, Henden A, Minnie S, Ensbey K, et al.
Blood
. 2019 Oct;
134(23):2092-2106.
PMID: 31578204
Graft-versus-host disease (GVHD) after allogeneic stem cell transplantation (alloSCT) is characterized by interleukin-6 (IL-6) dysregulation. IL-6 can mediate effects via various pathways, including classical, trans, and cluster signaling. Given the...
18.
Escrig A, Canal C, Sanchis P, Fernandez-Gayol O, Montilla A, Comes G, et al.
Brain Behav Immun
. 2019 Aug;
82:145-159.
PMID: 31401302
Alzheimer's disease (AD) is the most commonly diagnosed dementia but its underlying pathological mechanisms still unclear. Neuroinflammation and secretion of cytokines such as interleukin-6 (IL-6) accompany the main hallmarks of...
19.
Whitham M, Pal M, Petzold T, Hjorth M, Egan C, Brunner J, et al.
Am J Physiol Endocrinol Metab
. 2019 Aug;
317(4):E597-E604.
PMID: 31386565
It has been suggested that interleukin-6 (IL-6) produced by adipocytes in obesity leads to liver insulin resistance, although this hypothesis has never been definitively tested. Accordingly, we did so by...
20.
Fernandez-Gayol O, Sanchis P, Aguilar K, Navarro-Sempere A, Comes G, Molinero A, et al.
Neuroendocrinology
. 2019 Jan;
109(2):113-130.
PMID: 30636247
Background/aims: Interleukin-6 (IL-6) is a major cytokine controlling body weight and metabolism, at least in part through actions in the central nervous system (CNS) from local sources. Methods: We herewith...