Juan D Maya
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Explore the profile of Juan D Maya including associated specialties, affiliations and a list of published articles.
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26
Citations
220
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Recent Articles
1.
Moncada-Basualto M, Saavedra-Olavarria J, Rivero-Jerez P, Rojas C, Maya J, Liempi A, et al.
Molecules
. 2024 Jun;
29(12).
PMID: 38930828
The development of new compounds to treat Chagas disease is imperative due to the adverse effects of current drugs and their low efficacy in the chronic phase. This study aims...
2.
Burgess V, Maya J
Rev Argent Microbiol
. 2023 Apr;
55(3):278-288.
PMID: 37019801
Infections, including zoonoses, constitute a threat to human health due to the spread of resistant pathogens. These diseases generate an inflammatory response controlled by a resolving mechanism involving specialized membrane...
3.
Campos-Estrada C, Urarte E, Denegri M, Villalon L, Gonzalez-Herrera F, Kemmerling U, et al.
PLoS One
. 2023 Jan;
18(1):e0280335.
PMID: 36638112
Background: Cardiac complications, including heart failure and arrhythmias, are the leading causes of disability and death in Chagas disease (CD). CD, caused by the Trypanosoma cruzi parasite, afflicts 7 million...
4.
Quintero-Pertuz H, Veas-Albornoz R, Carrillo I, Gonzalez-Herrera F, Lapier M, Carbono-Delahoz E, et al.
Biomed Pharmacother
. 2022 Mar;
148:112761.
PMID: 35240521
The deficit of effective treatments for Chagas disease has led to searching for new substances with therapeutic potential. Natural products possess a wide variety of chemical structural motifs and are...
5.
Carrillo I, Nonato Rabelo R, Barbosa C, Rates M, Fuentes-Retamal S, Gonzalez-Herrera F, et al.
PLoS Negl Trop Dis
. 2021 Nov;
15(11):e0009978.
PMID: 34784372
Background: Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and is widely distributed worldwide because of migration. In 30% of cases, after years of infection...
6.
Lopez-Lira C, Tapia R, Herrera A, Lapier M, Maya J, Soto-Delgado J, et al.
Bioorg Chem
. 2021 Apr;
111:104823.
PMID: 33798844
Herein, the design and synthesis of new 2-phenyl(pyridinyl)benzimidazolequinones and their 5-phenoxy derivatives as potential anti-Trypanosoma cruzi agents are described. The compounds were evaluated in vitro against the epimastigotes and trypomastigote...
7.
Maya J, Lapier M, Castillo C, Kemmerling U, Campos-Estrada C, Lopez-Munoz R
Emerg Top Life Sci
. 2021 Feb;
1(6):579-584.
PMID: 33525838
Infectious diseases are the main cause of acquired dilated cardiomyopathy. This group of disorders shares in common inflammatory cell infiltrate and myocardial remodeling. As part of its pathophysiology, there is...
8.
Kemmerling U, Castillo C, Liempi A, Medina L, Carrillo I, Droguett D, et al.
Emerg Top Life Sci
. 2021 Feb;
1(6):573-577.
PMID: 33525837
Congenital Chagas disease, caused by Trypanosoma cruzi (T. cruzi), is partially responsible for the increasing globalization of Chagas disease despite its low transmission. During congenital transmission, the parasite reaches the...
9.
Lapier M, Ballesteros-Garrido R, Guzman-Rivera D, Gonzalez-Herrera F, Aguilera-Venegas B, Moncada-Basualto M, et al.
Future Med Chem
. 2019 Jul;
11(10):1137-1155.
PMID: 31280672
To study a new series of [1,2,3]triazolo[1,5-α]pyridine derivatives as trypanocidal agents because current antichagasic pharmacologic therapy is only partially effective. The effect of the series upon epimastigotes and murine macrophages...
10.
Lopez-Munoz R, Molina-Berrios A, Campos-Estrada C, Abarca-Sanhueza P, Urrutia-Llancaqueo L, Pena-Espinoza M, et al.
Front Microbiol
. 2018 Sep;
9:1961.
PMID: 30186271
Pathogenic trypanosomatids (, and spp.) are protozoan parasites that cause neglected diseases affecting millions of people in Africa, Asia, and the Americas. In the process of infection, trypanosomatids evade and...