Juan Castillo-Fernandez
Overview
Explore the profile of Juan Castillo-Fernandez including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
476
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Recent Articles
1.
Demond H, Khan S, Castillo-Fernandez J, Hanna C, Kelsey G
BMC Mol Cell Biol
. 2025 Jan;
26(1):2.
PMID: 39754059
Background: During the latter stages of their development, mammalian oocytes under dramatic chromatin reconfiguration, transitioning from a non-surrounded nucleolus (NSN) to a surrounded nucleolus (SN) stage, and concomitant transcriptional silencing....
2.
Whittle M, Castillo-Fernandez J, Amos G, Watson P
Sci Rep
. 2024 Aug;
14(1):20104.
PMID: 39209855
Furthering our knowledge of the skin microbiome is essential to understand health and disease in canines. To date, studies into the canine skin microbiome have focused on 16S rRNA high...
3.
Patel K, Hunt A, Castillo-Fernandez J, Abrams C, King T, Watson P, et al.
Sci Rep
. 2024 Aug;
14(1):18897.
PMID: 39143116
There is growing evidence that a relationship exists between mental and emotional wellbeing and the gut microbiota. Little is known regarding how the microbiota reacts to repeated acute stress events...
4.
Manickavel S, Glehn-Ponsirenas R, Gray J, Furuya Y, Fu D, Gulbahce N, et al.
Transpl Immunol
. 2024 May;
84:102055.
PMID: 38744349
Respiratory complications following allogeneic HSCT can lead to severe morbidity and mortality. Lung transplantation (LT) is a potential treatment for select patients with late-onset non-infectious pulmonary complications post-HSCT. Donor-derived cell-free...
5.
Marshall-Jones Z, Patel K, Castillo-Fernandez J, Lonsdale Z, Haydock R, Staunton R, et al.
Sci Rep
. 2024 Mar;
14(1):5277.
PMID: 38438389
Antibiotic resistance is recognised as one of the biggest global threats to human and animal health. Understanding the influence of antibiotics on the canine microbiome is important to know the...
6.
Villicana S, Castillo-Fernandez J, Hannon E, Christiansen C, Tsai P, Maddock J, et al.
Genome Biol
. 2023 Jul;
24(1):176.
PMID: 37525248
Background: Pinpointing genetic impacts on DNA methylation can improve our understanding of pathways that underlie gene regulation and disease risk. Results: We report heritability and methylation quantitative trait locus (meQTL)...
7.
McAllan L, Baranasic D, Villicana S, Brown S, Zhang W, Lehne B, et al.
Nat Commun
. 2023 May;
14(1):2784.
PMID: 37188674
DNA methylation variations are prevalent in human obesity but evidence of a causative role in disease pathogenesis is limited. Here, we combine epigenome-wide association and integrative genomics to investigate the...
8.
Demond H, Hanna C, Castillo-Fernandez J, Santos F, Papachristou E, Segonds-Pichon A, et al.
Genome Res
. 2023 Jan;
33(1):18-31.
PMID: 36690445
EHMT1 (also known as GLP) is a multifunctional protein, best known for its role as an H3K9me1 and H3K9me2 methyltransferase through its reportedly obligatory dimerization with EHMT2 (also known as...
9.
Christiansen C, Tomlinson M, Eliot M, Nilsson E, Costeira R, Xia Y, et al.
Genome Med
. 2022 Jul;
14(1):75.
PMID: 35843982
Background: There is considerable evidence for the importance of the DNA methylome in metabolic health, for example, a robust methylation signature has been associated with body mass index (BMI). However,...
10.
Lee M, Huan T, McCartney D, Chittoor G, de Vries M, Lahousse L, et al.
Am J Respir Crit Care Med
. 2022 May;
206(3):321-336.
PMID: 35536696
Methylation integrates factors present at birth and modifiable across the lifespan that can influence pulmonary function. Studies are limited in scope and replication. To conduct large-scale epigenome-wide meta-analyses of blood...