Josue de Moraes
Overview
Explore the profile of Josue de Moraes including associated specialties, affiliations and a list of published articles.
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Articles
91
Citations
961
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Recent Articles
1.
Cirino M, Teixeira T, Silva A, Borges A, Fukui-Silva L, Wagner L, et al.
Sci Rep
. 2025 Feb;
15(1):4699.
PMID: 39922838
Parasitic worm infections impose a significant public health burden, affecting over 2 billion people, particularly in low-income regions. The limited efficacy of current treatments highlights the urgent need for new...
2.
Umehara E, Cajas R, Conceicao G, Antar G, Andricopulo A, de Moraes J, et al.
Molecules
. 2025 Jan;
30(2).
PMID: 39860137
In the present study, the hexane extract from branches of (Winteraceae) displayed potent activity against parasites (100% mortality of the worms at 200 μg/mL). Bioactivity-guided fractionation afforded, in addition to...
3.
Ferreira E, Campos I, Cajas R, de Souza Costa D, Aleixo de Carvalho L, Fernandes da Costa Franklin P, et al.
Exp Parasitol
. 2025 Jan;
269:108897.
PMID: 39800044
Schistosomiasis stands as one of the most significant parasitic diseases on a global scale, with approximately 250 million infections worldwide. It is imperative to address this pressing issue by developing...
4.
Oliveira M, Dos S Andrade T, Junior J, Lima N, Machado H, Tabudravu J, et al.
J Nat Prod
. 2025 Jan;
88(2):255-261.
PMID: 39754587
With praziquantel being the sole available drug for schistosomiasis, identifying novel anthelmintic agents is imperative. A chemical investigation of the fruiting body of the bioluminescent mushroom Berk. resulted in the...
5.
de Souza Costa D, Cajas R, Leal C, Carvalho L, Souza L, Fukui-Silva L, et al.
J Ethnopharmacol
. 2024 Nov;
338(Pt 1):119028.
PMID: 39489364
Ethnopharmacological Relevance: Acmella oleracea (L.) R. K. Jansen, commonly referred to as "Jambu", is a valuable medicinal plant native to the Amazon regions. Inflorescences of A. oleracea is utilized as...
6.
Dantas A, Teixeira F, Oblitas R, Araujo W, Amaro M, Cajas R, et al.
Sci Rep
. 2024 Oct;
14(1):23055.
PMID: 39367249
Schistosoma mansoni, an intravascular parasitic worm and the causative agent of schistosomiasis, relies on its tegument (outer layer) for survival and host interaction. This study explored the morphology and mechanical...
7.
Souza D, Totini C, Cajas R, Teixeira T, Oliveira E, Cirino M, et al.
Phytomedicine
. 2024 Sep;
135:156045.
PMID: 39299096
Background: Schistosomiasis, caused by the parasitic blood fluke Schistosoma mansoni, is a significant global health concern, particularly in tropical and subtropical regions. The available chemotherapeutic drug is restricted to praziquantel...
8.
Umehara E, Teixeira T, Cajas R, Amaro M, de Moraes J, Lago J
Antibiotics (Basel)
. 2024 Aug;
13(8).
PMID: 39200079
Schistosomiasis, a neglected tropical disease impacting over 250 million individuals globally, remains a major public health challenge due to its prevalence and significant impact on affected communities. Praziquantel, the sole...
9.
Albuquerque M, Luz R, Rodrigues V, Roquini D, Umehara E, de Moraes J, et al.
Chem Biodivers
. 2024 Aug;
21(11):e202401452.
PMID: 39136606
Baccharis mattogrosensis is a species from Asteraceae which has been used in Brazilian folk medicine to treatment of several illnesses, including those caused by parasites. In the present work, the...
10.
Dobrachinski L, Ferreira L, Cirino M, Andrade-de-Siqueira A, Mafud A, Mascarenhas Y, et al.
Future Med Chem
. 2024 Jul;
16(17):1791-1799.
PMID: 39072451
To identify potential antischistosomal agents through 3D pharmacophore-based virtual screening of US FDA approved drugs. A comprehensive virtual screening was conducted on a dataset of 10,000 FDA approved drugs, employing...