Joshua M Nicholson
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Explore the profile of Joshua M Nicholson including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
476
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Recent Articles
1.
Nicholson J, Yang D, Koelblen T, Hu E, Coss C, Burris T, et al.
J Med Chem
. 2024 Sep;
67(18):16185-16194.
PMID: 39240657
Natural products are widely recognized as valuable starting points for the development of therapeutics, with synthetic tetracyclic triterpenoids (e.g., steroids) being the most well represented among the drugs approved by...
2.
Nicholson J, Micalizio G
Org Lett
. 2023 Jul;
25(30):5687-5691.
PMID: 37477981
Asymmetric syntheses of euphol and tirucallol have been accomplished by way of a concise sequence of chemical steps featuring several modern stereoselective transformations. The preparative solution described for these complex...
3.
Rutledge S, Douglas T, Nicholson J, Vila-Casadesus M, Kantzler C, Wangsa D, et al.
Sci Rep
. 2022 Aug;
12(1):14812.
PMID: 36045282
No abstract available.
4.
Nicholson J, Millham A, Bucknam A, Markham L, Sailors X, Micalizio G
J Org Chem
. 2022 Feb;
87(5):3352-3362.
PMID: 35175755
Tetracyclic terpenoid-derived natural products are a broad class of medically relevant agents that include well-known steroid hormones and related structures, as well as more synthetically challenging congeners such as limonoids,...
5.
Nicholson J, Uppala A, Sieber M, Grabitz P, Mordaunt M, Rife S
FEBS J
. 2020 Oct;
288(14):4242-4248.
PMID: 33089957
Wikipedia is a widely used online reference work which cites hundreds of thousands of scientific articles across its entries. The quality of these citations has not been previously measured, and...
6.
Baudoin N, Nicholson J, Soto K, Martin O, Chen J, Cimini D
Elife
. 2020 Apr;
9.
PMID: 32347795
Tetraploidy has long been of interest to both cell and cancer biologists, partly because of its documented role in tumorigenesis. A common model proposes that the extra centrosomes that are...
7.
Rutledge S, Douglas T, Nicholson J, Vila-Casadesus M, Kantzler C, Wangsa D, et al.
Sci Rep
. 2016 Mar;
6:22828.
PMID: 26956415
An abnormal chromosome number, a condition known as aneuploidy, is a ubiquitous feature of cancer cells. A number of studies have shown that aneuploidy impairs cellular fitness. However, there is...
8.
Nicholson J, Macedo J, Mattingly A, Wangsa D, Camps J, Lima V, et al.
Elife
. 2015 May;
4.
PMID: 25942454
Cancer cells display aneuploid karyotypes and typically mis-segregate chromosomes at high rates, a phenotype referred to as chromosomal instability (CIN). To test the effects of aneuploidy on chromosome segregation and...
9.
Nicholson J, Cimini D
Int Rev Cell Mol Biol
. 2015 Feb;
315:299-317.
PMID: 25708466
Aneuploidy is widely acknowledged as a leading cause of miscarriage and birth defects in humans, and is generally known to be deleterious to the survival of individual cells. However, aneuploidy...
10.
Bakhoum S, Silkworth W, Nardi I, Nicholson J, Compton D, Cimini D
Curr Biol
. 2014 Feb;
24(4):R148-9.
PMID: 24556433
No abstract available.