Joshua L Dunaief
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Explore the profile of Joshua L Dunaief including associated specialties, affiliations and a list of published articles.
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135
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4677
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Recent Articles
1.
Guo M, Schwartz T, Lawrence E, Lu J, Zhong A, Wu J, et al.
Exp Eye Res
. 2025 Mar;
254:110325.
PMID: 40058724
Monocyte chemoattractant protein-1 (MCP-1)/CCL2, a potent chemokine for myeloid cells, has been associated with disease progression in glaucoma. We examined whether genetic knockout (KO) of MCP-1 affected RGC density and...
2.
Anderson B, Bell B, Song Y, Lee T, Wang T, Dunaief J
Transl Vis Sci Technol
. 2025 Jan;
14(1):9.
PMID: 39792055
Purpose: Geographic atrophy (GA), an advanced form of dry age-related macular degeneration (AMD), has limited treatment options. This study introduces a novel mouse model featuring an expanding GA patch that...
3.
Lee T, Bell B, Song Y, Dunaief J
Exp Eye Res
. 2024 Dec;
251:110221.
PMID: 39710099
Previously, we found that retinas of young male mice were more damaged than those of young female mice in the sodium iodate (NaIO) model. The purpose of this study was...
4.
Wang T, Song Y, Bell B, Anderson B, Lee T, Yu W, et al.
Exp Eye Res
. 2024 Nov;
250:110161.
PMID: 39557279
Complement factor 3 (C3) has emerged as a primary therapeutic target in age-related macular degeneration (AMD) supported by genetic, histologic, and clinical trial evidence. Yet, the site(s) of action are...
5.
Wojciechowski A, Bell B, Song Y, Anderson B, Conomikes A, Petruconis C, et al.
Exp Eye Res
. 2024 Aug;
247:110028.
PMID: 39128667
Age-related macular degeneration (AMD) is one of the leading causes of vision loss in the elderly. This disease involves oxidative stress burden in the retina leading to death of retinal...
6.
Bell B, Kaul C, Dunaief J, Hollyfield J, Bonilha V
Front Ophthalmol (Lausanne)
. 2024 May;
3.
PMID: 38689597
Ophthalmic imaging instruments, including the confocal scanning laser ophthalmoscope and spectral-domain optical coherence tomography system, originally intended for revealing ocular microstructures in the human eye, have been deployed by vision...
7.
Lee T, Bell B, Anderson B, Song Y, Dunaief J
Exp Eye Res
. 2024 Apr;
242:109879.
PMID: 38570182
Because the selective estrogen receptor modulator tamoxifen was shown to be retina-protective in the light damage and rd10 models of retinal degeneration, the purpose of this study was to test...
8.
Anderson B, Lee T, Bell B, Wang T, Dunaief J
Exp Eye Res
. 2023 Dec;
239:109772.
PMID: 38158173
Sodium iodate (NaIO) is a commonly used model for age-related macular degeneration (AMD), but its rapid and severe induction of retinal pigment epithelial (RPE) and photoreceptor degeneration can lead to...
9.
Anderson B, Lee T, Bell B, Song Y, Dunaief J
Dis Model Mech
. 2023 Jul;
16(7).
PMID: 37439255
In a previous report, a 39-year-old patient with high serum iron levels from hereditary hemochromatosis (HH) was diagnosed with a form of retinal degeneration called bull's eye maculopathy. This is...
10.
Zhang K, Jankowski C, Marshall R, Nair R, Mas Gomez N, Alnemri A, et al.
Dis Model Mech
. 2023 Jul;
16(7).
PMID: 37401371
Oxidative stress has been implicated in the pathogenesis of age-related macular degeneration, the leading cause of blindness in older adults, with retinal pigment epithelium (RPE) cells playing a key role....