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Joshua J Thompson

Explore the profile of Joshua J Thompson including associated specialties, affiliations and a list of published articles. Areas
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Citations 193
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Recent Articles
1.
Thompson J, McGovern J, Roxburgh C, Edwards J, Dolan R, McMillan D
Crit Rev Oncol Hematol . 2024 May; 199:104378. PMID: 38754770
Introduction: Cancer cachexia is a clinical condition characterized by recognizable "sickness behaviors" accompanied by loss of lean body tissue. The Global Leadership on Malnutrition (GLIM) has proposed phenotypic (unintentional weight...
2.
Pilat J, Brown R, Chen Z, Berle N, Othon A, Washington M, et al.
J Clin Invest . 2023 May; 133(13). PMID: 37166989
Although selenium deficiency correlates with colorectal cancer (CRC) risk, the roles of the selenium-rich antioxidant selenoprotein P (SELENOP) in CRC remain unclear. In this study, we defined SELENOP's contributions to...
3.
Thompson J, Koch R, Keedy V, Magge D
World J Surg Oncol . 2023 Jan; 21(1):24. PMID: 36710330
Synovial sarcoma is a rare soft tissue sarcoma which frequently involves the upper or lower extremities. Soft tissue sarcomas including synovial sarcoma have a propensity to metastasize to the lungs,...
4.
Thompson J, Short S, Parang B, Brown R, Li C, Ng V, et al.
Carcinogenesis . 2019 Jan; 40(9):1086-1098. PMID: 30689807
Blood vessel epicardial substance (BVES, otherwise known as POPDC1) is an integral membrane protein known to regulate tight junction formation and epithelial-mesenchymal transition. BVES is underexpressed in a number of...
5.
Short S, Thompson J, Bilotta A, Chen X, Revetta F, Washington M, et al.
Mol Cancer Res . 2019 Jan; 17(4):882-894. PMID: 30655319
Serine threonine kinase 17A (STK17A) is a ubiquitously expressed kinase originally identified as a regulator of apoptosis; however, whether it functionally contributes to colorectal cancer has not been established. Here,...
6.
Parang B, Thompson J, Williams C
Tissue Barriers . 2018 Oct; 6(4):1-12. PMID: 30307367
Blood vessel epicardial substance (BVES) is a tight-junction associated protein that was originally discovered from a cDNA screen of the developing heart. Research over the last decade has shown that...
7.
Choksi Y, K Reddy V, Singh K, Barrett C, Short S, Parang B, et al.
Mucosal Immunol . 2018 Jun; 11(5):1363-1374. PMID: 29907869
Blood vessel epicardial substance (BVES), or POPDC1, is a tight junction-associated transmembrane protein that modulates epithelial-to-mesenchymal transition (EMT) via junctional signaling pathways. There have been no in vivo studies investigating...
8.
Saito-Diaz K, Benchabane H, Tiwari A, Tian A, Li B, Thompson J, et al.
Dev Cell . 2018 Mar; 44(5):566-581.e8. PMID: 29533772
Adenomatous polyposis coli (APC) mutations cause Wnt pathway activation in human cancers. Current models for APC action emphasize its role in promoting β-catenin degradation downstream of Wnt receptors. Unexpectedly, we...
9.
Thompson J, Williams C
Genes (Basel) . 2018 Mar; 9(3). PMID: 29495399
Protein phosphorylation is a ubiquitous cellular process that allows for the nuanced and reversible regulation of protein activity. Protein phosphatase 2A (PP2A) is a heterotrimeric serine-threonine phosphatase-composed of a structural,...
10.
McDonough E, Barrett C, Parang B, Mittal M, Smith J, Bradley A, et al.
JCI Insight . 2017 Aug; 2(16). PMID: 28814670
MTG16 is a member of the myeloid translocation gene (MTG) family of transcriptional corepressors. While MTGs were originally identified in chromosomal translocations in acute myeloid leukemia, recent studies have uncovered...