Joshua D Stender
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Explore the profile of Joshua D Stender including associated specialties, affiliations and a list of published articles.
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20
Citations
1846
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Recent Articles
1.
Abe Y, Kofman E, Ouyang Z, Cruz-Becerra G, Spann N, Seidman J, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(2):e2316104121.
PMID: 38165941
The nuclear receptor corepressor (NCoR) forms a complex with histone deacetylase 3 (HDAC3) that mediates repressive functions of unliganded nuclear receptors and other transcriptional repressors by deacetylation of histone substrates....
2.
Abe Y, Kofman E, Almeida M, Ouyang Z, Ponte F, Mueller J, et al.
Mol Cell
. 2023 Sep;
83(19):3421-3437.e11.
PMID: 37751740
The nuclear receptor co-repressor (NCoR) complex mediates transcriptional repression dependent on histone deacetylation by histone deacetylase 3 (HDAC3) as a component of the complex. Unexpectedly, we found that signaling by...
3.
Stolzenburg L, Esmaeeli S, Kulkarni A, Murphy E, Kwon T, Preiss C, et al.
PLoS One
. 2023 Sep;
18(9):e0291029.
PMID: 37751459
Neurodegenerative diseases encompass a group of debilitating conditions resulting from progressive nerve cell death. Of these, Alzheimer's disease (AD) occurs most frequently, but is currently incurable and has limited treatment...
4.
Kastrati I, Joosten S, Semina S, Alejo L, Brovkovych S, Stender J, et al.
Mol Cancer Res
. 2020 Apr;
18(7):1018-1027.
PMID: 32245803
The purpose of this study was to identify critical pathways promoting survival of tamoxifen-tolerant, estrogen receptor α positive (ER) breast cancer cells, which contribute to therapy resistance and disease recurrence....
5.
Cohen Katsenelson K, Stender J, Kawashima A, Lorden G, Uchiyama S, Nizet V, et al.
Elife
. 2019 Aug;
8.
PMID: 31408005
Inflammation is an essential aspect of innate immunity but also contributes to diverse human diseases. Although much is known about the kinases that control inflammatory signaling, less is known about...
6.
Fonseca G, Tao J, Westin E, Duttke S, Spann N, Strid T, et al.
Nat Commun
. 2019 Jan;
10(1):414.
PMID: 30679424
Mechanisms by which members of the AP-1 family of transcription factors play non-redundant biological roles despite recognizing the same DNA sequence remain poorly understood. To address this question, here we...
7.
Speltz T, Danes J, Stender J, Frasor J, Moore T
ACS Chem Biol
. 2018 Jan;
13(3):676-684.
PMID: 29309722
We and others have proposed that coactivator binding inhibitors, which block the interaction of estrogen receptor and steroid receptor coactivators, may represent a potential class of new breast cancer therapeutics....
8.
Stender J, Nwachukwu J, Kastrati I, Kim Y, Strid T, Yakir M, et al.
Mol Cell
. 2017 Mar;
65(6):1122-1135.e5.
PMID: 28306507
Human breast cancers that exhibit high proportions of immune cells and elevated levels of pro-inflammatory cytokines predict poor prognosis. Here, we demonstrate that treatment of human MCF-7 breast cancer cells...
9.
Meitinger F, Anzola J, Kaulich M, Richardson A, Stender J, Benner C, et al.
J Cell Biol
. 2016 Jul;
214(2):155-66.
PMID: 27432897
In normal human cells, centrosome loss induced by centrinone-a specific centrosome duplication inhibitor-leads to irreversible, p53-dependent G1 arrest by an unknown mechanism. A genome-wide CRISPR/Cas9 screen for centrinone resistance identified...
10.
Gosselin D, Link V, Romanoski C, Fonseca G, Eichenfield D, Spann N, et al.
Cell
. 2014 Dec;
159(6):1327-40.
PMID: 25480297
Macrophages reside in essentially all tissues of the body and play key roles in innate and adaptive immune responses. Distinct populations of tissue macrophages also acquire context-specific functions that are...