Josh T Cuperus
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Explore the profile of Josh T Cuperus including associated specialties, affiliations and a list of published articles.
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1910
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Recent Articles
31.
Carbonell A, Takeda A, Fahlgren N, Johnson S, Cuperus J, Carrington J
Plant Physiol
. 2014 Mar;
165(1):15-29.
PMID: 24647477
Artificial microRNAs (amiRNAs) and synthetic trans-acting small interfering RNAs (syn-tasiRNAs) are used for small RNA-based, specific gene silencing or knockdown in plants. Current methods to generate amiRNA or syn-tasiRNA constructs...
32.
Fahlgren N, Bollmann S, Kasschau K, Cuperus J, Press C, Sullivan C, et al.
PLoS One
. 2013 Nov;
8(10):e77181.
PMID: 24204767
In eukaryotes, RNA silencing pathways utilize 20-30-nucleotide small RNAs to regulate gene expression, specify and maintain chromatin structure, and repress viruses and mobile genetic elements. RNA silencing was likely present...
33.
Carbonell A, Fahlgren N, Garcia-Ruiz H, Gilbert K, Montgomery T, Nguyen T, et al.
Plant Cell
. 2012 Oct;
24(9):3613-29.
PMID: 23023169
In RNA-directed silencing pathways, ternary complexes result from small RNA-guided ARGONAUTE (AGO) associating with target transcripts. Target transcripts are often silenced through direct cleavage (slicing), destabilization through slicer-independent turnover mechanisms,...
34.
Cuperus J, Fahlgren N, Carrington J
Plant Cell
. 2011 Feb;
23(2):431-42.
PMID: 21317375
MicroRNAs (miRNAs) are small regulatory RNAs found in diverse eukaryotic lineages. In plants, a minority of annotated MIRNA gene families are conserved between plant families, while the majority are family-...
35.
Greenberg M, Ausin I, Chan S, Cokus S, Cuperus J, Feng S, et al.
Epigenetics
. 2010 Dec;
6(3):344-54.
PMID: 21150311
De novo DNA methylation in Arabidopsis thaliana is catalyzed by the methyltransferase DRM2, a homolog of the mammalian de novo methyltransferase DNMT3. DRM2 is targeted to DNA by small interfering...
36.
Cuperus J, Carbonell A, Fahlgren N, Garcia-Ruiz H, Burke R, Takeda A, et al.
Nat Struct Mol Biol
. 2010 Jun;
17(8):997-1003.
PMID: 20562854
RNA interference pathways can involve amplification of secondary siRNAs by RNA-dependent RNA polymerases. In plants, RDR6-dependent secondary siRNAs arise from transcripts targeted by some microRNAs (miRNAs). Here, Arabidopsis thaliana secondary...
37.
Cuperus J, Montgomery T, Fahlgren N, Burke R, Townsend T, Sullivan C, et al.
Proc Natl Acad Sci U S A
. 2009 Dec;
107(1):466-71.
PMID: 20018656
Transacting siRNA (tasiRNA) biogenesis in Arabidopsis is initiated by microRNA (miRNA) -guided cleavage of primary transcripts. In the case of TAS3 tasiRNA formation, ARGONAUTE7 (AGO7)-miR390 complexes interact with primary transcripts...
38.
Montgomery T, Howell M, Cuperus J, Li D, Hansen J, Alexander A, et al.
Cell
. 2008 Mar;
133(1):128-41.
PMID: 18342362
Trans-acting siRNA form through a refined RNAi mechanism in plants. miRNA-guided cleavage triggers entry of precursor transcripts into an RNA-DEPENDENT RNA POLYMERASE6 pathway, and sets the register for phased tasiRNA...
39.
Lee H, Humann J, Pitrak J, Cuperus J, Dawn Parks T, Whistler C, et al.
Plant Physiol
. 2003 Sep;
133(3):966-77.
PMID: 12972655
Agrobacterium tumefaciens oncogenes cause transformed plant cells to overproduce auxin and cytokinin. Two oncogenes encode enzymes that convert tryptophan to indole-3-acetic acid (auxin): iaaM (tryptophan mono-oxygenase) and iaaH (indole-3-acetamide hydrolase)....