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Josh J Friesen

Explore the profile of Josh J Friesen including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Casmil I, Bathula N, Huang C, Wayne C, Cairns E, Friesen J, et al.
Mol Ther . 2025 Jan; 33(2):514-528. PMID: 39741413
Self-amplifying RNA (saRNA) vectors are a next-generation RNA technology that extends the expression of heterologous genes. Clinical trials have shown the dose-sparing capacity of saRNA vectors in a vaccine context...
2.
Bathula N, Friesen J, Casmil I, Wayne C, Liao S, Soriano S, et al.
J Control Release . 2024 Aug; 374:28-38. PMID: 39097193
Self-amplifying RNA (saRNA) is a next-generation RNA platform derived from an alphavirus that enables replication in host cytosol, offering a promising shift from traditional messenger RNA (mRNA) therapies by enabling...
3.
Friesen J, Blakney A
J Gene Med . 2024 Feb; 26(2):e3672. PMID: 38380796
Ribonucleic acid (RNA) has emerged as one of the most promising therapeutic payloads in the field of gene therapy. There are many unique types of RNA that allow for a...