Josephine Mun Yee Ko
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Explore the profile of Josephine Mun Yee Ko including associated specialties, affiliations and a list of published articles.
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31
Citations
743
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Recent Articles
1.
Ng H, Ko J, Lam K, Kwong D, Lo A, Wong I, et al.
JAMA Surg
. 2023 Sep;
158(11):1141-1150.
PMID: 37728901
Importance: Esophageal squamous cell carcinoma (ESCC) is a deadly disease with frequent recurrence. There are unmet needs for prognostic biomarkers for dynamically monitoring disease progression and detecting minimal residual disease....
2.
Ko J, Lam K, Kwong D, Wong I, Chan F, Wong C, et al.
Cancers (Basel)
. 2023 Feb;
15(3).
PMID: 36765790
We aim to reveal the clinical significance and potential usefulness of dynamic monitoring of CTCs to track therapeutic responses and improve survival for advanced ESCC patients. Peripheral blood (PB) (...
3.
Ko J, Lam S, Ning L, Chai A, Lei L, Choi S, et al.
Cancers (Basel)
. 2021 Sep;
13(18).
PMID: 34572942
Unbiased whole-exome sequencing approaches in familial esophageal squamous cell carcinoma (ESCC) initially prioritized as a candidate cancer predisposition gene. The combined study with 3289 Henan individuals from Northern China identified...
4.
Lei L, Yu V, Ko J, Ning L, Lung M
Cancers (Basel)
. 2020 Sep;
12(9).
PMID: 32906798
Fanconi anemia patients with germline genetic defects in are highly susceptible to cancers. Esophageal squamous cell carcinoma (ESCC) is a deadly cancer. Little is known about the function of in...
5.
Ko J, Ng H, Lam K, Chiu K, Kwong D, Lo A, et al.
Cancers (Basel)
. 2020 May;
12(6).
PMID: 32466419
(1) Background: Early predictive markers to track treatment responses are needed for advanced esophageal squamous cell carcinoma (ESCC) patients. We examined the prognostication and risk stratification role of liquid biopsy...
6.
Yu V, Ko J, Ning L, Dai W, Law S, Lung M
Cancer Lett
. 2019 Jul;
461:56-64.
PMID: 31319137
Esophageal squamous cell carcinoma (ESCC) is a deadly disease with dismal 5-year survival. Extracellular matrix protein 1 (ECM1) was identified as one of the most downregulated genes by transcriptomic analysis...
7.
Leong M, Cheung A, Dai W, Tsao S, Tsang C, Dawson C, et al.
Proc Natl Acad Sci U S A
. 2019 Jun;
116(28):14144-14153.
PMID: 31235597
Epstein-Barr virus (EBV) induces histone modifications to regulate signaling pathways involved in EBV-driven tumorigenesis. To date, the regulatory mechanisms involved are poorly understood. In this study, we show that EBV...
8.
Lin W, Yip Y, Jia L, Deng W, Zheng H, Dai W, et al.
Nat Commun
. 2018 Nov;
9(1):4663.
PMID: 30405107
The lack of representative nasopharyngeal carcinoma (NPC) models has seriously hampered research on EBV carcinogenesis and preclinical studies in NPC. Here we report the successful growth of five NPC patient-derived...
9.
Ng H, Li J, Tao L, Lam A, Chan K, Ko J, et al.
Transl Oncol
. 2018 Sep;
11(6):1323-1333.
PMID: 30172884
The current study reveals the clinicopathological association of PD-L1 in Hong Kong esophageal squamous cell carcinoma (ESCC) patients and the differential regulation of PD-L1 by standard first-line chemotherapy in ESCC....
10.
Chai A, Cheung A, Dai W, Ko J, Lee N, Chan K, et al.
Cancer Biomark
. 2017 Dec;
21(3):583-590.
PMID: 29278876
Background: Nidogen-2 (NID2), a secretory basement membrane protein, has been implicated as a potential biomarker in ovarian cancer and hepatocellular carcinoma. Objective: In this study, we aimed to investigate the...