Josephine Mun Yee Ko
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Explore the profile of Josephine Mun Yee Ko including associated specialties, affiliations and a list of published articles.
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31
Citations
743
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Recent Articles
11.
Dai W, Ko J, Choi S, Yu Z, Ning L, Zheng H, et al.
J Pathol
. 2017 Jun;
242(4):500-510.
PMID: 28608921
Oesophageal squamous cell carcinoma (ESCC) is one of the most lethal cancers, owing to a high frequency of metastasis. However, little is known about the genomic landscape of metastatic ESCC....
12.
Chai A, Cheung A, Dai W, Ko J, Ip J, Chan K, et al.
Oncotarget
. 2016 Oct;
7(48):78859-78871.
PMID: 27793011
Nidogen-2 (NID2) is a key component of the basement membrane that stabilizes the extracellular matrix (ECM) network. The aim of the study is to analyze the functional roles of NID2...
13.
Zheng H, Dai W, Cheung A, Ko J, Kan R, Wong B, et al.
Proc Natl Acad Sci U S A
. 2016 Sep;
113(40):11283-11288.
PMID: 27647909
Nasopharyngeal carcinoma (NPC) is an epithelial malignancy with a unique geographical distribution. The genomic abnormalities leading to NPC pathogenesis remain unclear. In total, 135 NPC tumors were examined to characterize...
14.
Ip J, Ko J, Yu V, Chan K, Lam A, Law S, et al.
Biomed Res Int
. 2016 Jul;
2016:2348673.
PMID: 27462607
[This corrects the article DOI: 10.1155/2015/910715.].
15.
Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinoma
Dai W, Zheng H, Cheung A, Tang C, Ko J, Wong B, et al.
Proc Natl Acad Sci U S A
. 2016 Mar;
113(12):3317-22.
PMID: 26951679
Multiple factors, including host genetics, environmental factors, and Epstein-Barr virus (EBV) infection, contribute to nasopharyngeal carcinoma (NPC) development. To identify genetic susceptibility genes for NPC, a whole-exome sequencing (WES) study...
16.
Cheung A, Ip J, Chu A, Cheng Y, Leong M, Ko J, et al.
Oncotarget
. 2015 May;
6(15):13434-47.
PMID: 25970784
Protein Tyrosine Phosphatase, Receptor Type G (PTPRG) was identified as a candidate tumor suppressor gene in nasopharyngeal carcinoma (NPC). PTPRG induces significant in vivo tumor suppression in NPC. We identified...
17.
Dai W, Cheung A, Ko J, Cheng Y, Zheng H, Ngan R, et al.
Cancer Med
. 2015 May;
4(7):1079-90.
PMID: 25924914
Altered patterns of DNA methylation are key features of cancer. Nasopharyngeal carcinoma (NPC) has the highest incidence in Southern China. Aberrant methylation at the promoter region of tumor suppressors is...
18.
Ip J, Ko J, Yu V, Chan K, Lam A, Law S, et al.
Biomed Res Int
. 2015 Apr;
2015:910715.
PMID: 25834829
Increasing evidence indicates tumor-stromal interactions play a crucial role in cancer. An in vivo esophageal squamous cell carcinoma (ESCC) orthotopic animal model was developed with bioluminescence imaging established with a...
19.
Lung M, Cheung A, Ko J, Lung H, Cheng Y, Dai W
Chin J Cancer
. 2014 Nov;
33(11):556-68.
PMID: 25367335
The interplay between host cell genetics and Epstein-Barr virus (EBV) infection contributes to the development of nasopharyngeal carcinoma (NPC). Understanding the host genetic and epigenetic alterations and the influence of...
20.
Ko J, Dai W, Wun Wong E, Kwong D, Ng W, Lee A, et al.
Int J Cancer
. 2014 Mar;
135(7):1634-45.
PMID: 24615621
The genetic etiology of nasopharyngeal carcinoma (NPC) and mechanisms for inherited susceptibility remain unclear. To examine genetic risk factors for NPC, we hypothesized that heritable risk is attributable to cumulative...