Josephine Forde-Thomas
Overview
Explore the profile of Josephine Forde-Thomas including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
49
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0
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Recent Articles
1.
Schiedel M, McArdle D, Padalino G, Chan A, Forde-Thomas J, McDonough M, et al.
J Med Chem
. 2023 Dec;
66(23):15801-15822.
PMID: 38048437
Schistosomiasis is a disease affecting >200 million people worldwide, but its treatment relies on a single agent, praziquantel. To investigate new avenues for schistosomiasis control, we have conducted the first...
2.
Padalino G, Celatka C, Rienhoff Jr H, Kalin J, Cole P, Lassalle D, et al.
Wellcome Open Res
. 2023 Jul;
8:146.
PMID: 37520936
: , a parasitic worm species responsible for the neglected tropical disease schistosomiasis, undergoes strict developmental regulation of gene expression that is carefully controlled by both genetic and epigenetic processes....
3.
Chakroborty A, Pritchard D, Bouillon M, Cervi A, Cookson A, Wild C, et al.
Vet Parasitol
. 2022 Aug;
309:109766.
PMID: 35926239
Control of liver fluke infections remains a significant challenge in the livestock sector due to widespread distribution of drug resistant parasite populations. In particular, increasing prevalence and economic losses due...
4.
Padalino G, El-Sakkary N, Liu L, Liu C, Harte D, Barnes R, et al.
Eur J Med Chem
. 2021 Sep;
226:113823.
PMID: 34536671
Schistosomiasis is a neglected disease of poverty that is caused by infection with blood fluke species contained within the genus Schistosoma. For the last 40 years, control of schistosomiasis in...
5.
Webb L, Phythian-Adams A, Costain A, Brown S, Lundie R, Forde-Thomas J, et al.
Immunohorizons
. 2021 Aug;
5(8):721-732.
PMID: 34462311
Plasmacytoid dendritic cells (pDCs) are potent producers of type I IFN (IFN-I) during viral infection and respond to IFN-I in a positive feedback loop that promotes their function. IFN-I shapes...
6.
Partridge F, Bataille C, Forman R, Marriott A, Forde-Thomas J, Haberli C, et al.
ACS Infect Dis
. 2021 Apr;
7(5):1260-1274.
PMID: 33797218
Nine hundred million people are infected with the soil-transmitted helminths (roundworm), hookworm, and (whipworm). However, low single-dose cure rates of the benzimidazole drugs, the mainstay of preventative chemotherapy for whipworm,...
7.
Perally S, Geyer K, Farani P, Chalmers I, Fernandez-Fuentes N, Maskell D, et al.
Int J Parasitol
. 2020 Nov;
51(4):251-261.
PMID: 33253697
The Schistosoma mansoni venom allergen-like protein (SmVAL) superfamily is a collection of at least 29 molecules that have been classified into two distinctive groups (Group 1 and Group 2 SmVALs)....
8.
Whiteland H, Crusco A, Bloemberg L, Tibble-Howlings J, Forde-Thomas J, Coghlan A, et al.
PLoS Negl Trop Dis
. 2020 Oct;
14(10):e0008630.
PMID: 33075069
Background: Schistosomiasis is a prevalent neglected tropical disease that affects approximately 300 million people worldwide. Its treatment is through a single class chemotherapy, praziquantel. Concerns surrounding the emergence of praziquantel...
9.
Whatley K, Padalino G, Whiteland H, Geyer K, Hulme B, Chalmers I, et al.
PLoS Negl Trop Dis
. 2019 Nov;
13(11):e0007693.
PMID: 31730617
Background: Praziquantel represents the frontline chemotherapy used to treat schistosomiasis, a neglected tropical disease (NTD) caused by infection with macro-parasitic blood fluke schistosomes. While this drug is safe, its inability...