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Joseph T Rodgers

Explore the profile of Joseph T Rodgers including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 6256
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Recent Articles
1.
Zhou H, Nguyen L, Arnesano C, Ando Y, Raval M, Rodgers J, et al.
iScience . 2020 Jan; 23(2):100831. PMID: 31982780
Metabolism is a key regulator of hematopoietic stem cell (HSC) functions. There is a lack of real-time, non-invasive approaches to evaluate metabolism in single HSCs. Using fluorescence lifetime imaging microscopy,...
2.
Haller S, Kapuria S, Riley R, OLeary M, Schreiber K, Andersen J, et al.
Cell Stem Cell . 2017 Dec; 21(6):806-818.e5. PMID: 29220665
The balance between self-renewal and differentiation ensures long-term maintenance of stem cell (SC) pools in regenerating epithelial tissues. This balance is challenged during periods of high regenerative pressure and is...
3.
Rodgers J, Schroeder M, Ma C, Rando T
Cell Rep . 2017 Apr; 19(3):479-486. PMID: 28423312
The activation of quiescent stem cells into the cell cycle is a key step in initiating the process of tissue repair. We recently reported that quiescent stem cells can transition...
4.
Rodgers J
Cell Stem Cell . 2016 Aug; 19(2):150-151. PMID: 27494671
Following an injury, the extracellular matrix (ECM) undergoes dramatic remodeling to facilitate tissue repair. In a new study, Lukjanenko and colleagues show how an age-associated change in this process affects...
5.
Rodgers J, King K, Brett J, Cromie M, Charville G, Maguire K, et al.
Nature . 2014 May; 510(7505):393-6. PMID: 24870234
A unique property of many adult stem cells is their ability to exist in a non-cycling, quiescent state. Although quiescence serves an essential role in preserving stem cell function until...
6.
Kraus D, Yang Q, Kong D, Banks A, Zhang L, Rodgers J, et al.
Nature . 2014 Apr; 508(7495):258-62. PMID: 24717514
In obesity and type 2 diabetes, Glut4 glucose transporter expression is decreased selectively in adipocytes. Adipose-specific knockout or overexpression of Glut4 alters systemic insulin sensitivity. Here we show, using DNA...
7.
Hall J, Tabata M, Rodgers J, Puigserver P
Mol Endocrinol . 2014 Apr; 28(6):912-24. PMID: 24694308
Hepatic forkhead protein FoxO1 is a key component of systemic glucose homeostasis via its ability to regulate the transcription of rate-limiting enzymes in gluconeogenesis. Important in the regulation of FoxO1...
8.
Tabata M, Rodgers J, Hall J, Lee Y, Jedrychowski M, Gygi S, et al.
Diabetes . 2014 Jan; 63(5):1519-32. PMID: 24458359
Hepatic ketogenesis plays an important role in catabolism of fatty acids during fasting along with dietary lipid overload, but the mechanisms regulating this process remain poorly understood. Here, we show...
9.
Rodgers J, Rando T
EMBO J . 2012 Oct; 31(21):4103-5. PMID: 23042560
No abstract available.
10.
Rodgers J, Vogel R, Puigserver P
Mol Cell . 2011 Feb; 41(4):471-9. PMID: 21329884
Akt mediates important cellular decisions involved in growth, survival, and metabolism. The mechanisms by which Akt is phosphorylated and activated in response to growth factors or insulin have been extensively...