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Joseph R Rouse

Explore the profile of Joseph R Rouse including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 7
Followers 0
Related Specialties
General Medicine
Science
Infectious Diseases
Top 10 Co-Authors
Amanda Wahhab
Robert B Lochhead
Rebecca Danner
Klemen Strle
Brandon L Jutras
Michaela Pereckas
Mecaila E McClune
Lauren G Hackner
Jules M Dressler
Allen C Steere
Published In
Res Sq
ACR Open Rheumatol
bioRxiv
J Infect Dis
Arthritis Res Ther
Affiliations
Soon will be listed here.
Recent Articles
1.
An influenza mRNA vaccine protects ferrets from lethal infection with highly pathogenic avian influenza A(H5N1) virus
Hatta M, Hatta Y, Choi A, Hossain J, Feng C, Keller M, et al.
Sci Transl Med . 2024 Dec; 16(778):eads1273. PMID: 39693411
The global spread of the highly pathogenic avian influenza (HPAI) A(H5N1) virus poses a serious pandemic threat, necessitating the swift development of effective vaccines. The success of messenger RNA (mRNA)...
2.
Identification of Major Histocompatibility Complex Class II Epitopes From Lyme Autoantigen Apolipoprotein B-100 and Borrelia burgdorferi Mcp4 in Murine Lyme Arthritis
Danner R, Prochniak L, Pereckas M, Rouse J, Wahhab A, Hackner L, et al.
J Infect Dis . 2024 Aug; 230(Supplement_1):S27-S39. PMID: 39140726
Background: During infection with the Lyme arthritis (LA) pathogen Borrelia burgdorferi, T-cell responses to both host and pathogen are dysregulated, resulting in chronic infection and frequent development of autoimmunity. Methods:...
3.
HLA-DR-Expressing Fibroblast-Like Synoviocytes Are Inducible Antigen Presenting Cells That Present Autoantigens in Lyme Arthritis
Rouse J, Danner R, Wahhab A, Pereckas M, Nguyen C, McClune M, et al.
ACR Open Rheumatol . 2024 Jul; 6(10):678-689. PMID: 39073021
Objective: HLA-DR-expressing fibroblast-like synoviocytes (FLS) are a prominent cell type in synovial tissue in chronic inflammatory forms of arthritis. FLS-derived extracellular matrix (ECM) proteins, including fibronectin-1 (FN1), contain immunogenic CD4+...
4.
Peptidoglycan in osteoarthritis synovial tissue is associated with joint inflammation
Holub M, Wahhab A, Rouse J, Danner R, Hackner L, Duris C, et al.
Arthritis Res Ther . 2024 Mar; 26(1):77. PMID: 38532447
Objectives: Peptidoglycan (PG) is an arthritogenic bacterial cell wall component whose role in human osteoarthritis is poorly understood. The purpose of this study was to determine if PG is present...
5.
Human leukocyte antigen HLA-DR-expressing fibroblast-like synoviocytes are inducible antigen presenting cells that present autoantigens in Lyme arthritis
Rouse J, Danner R, Wahhab A, Pereckas M, McClune M, Steere A, et al.
bioRxiv . 2023 Dec; PMID: 38045407
Background: HLA-DR-expressing fibroblast-like synoviocytes (FLS) are a prominent cell type in synovial tissue in chronic inflammatory forms of arthritis. We recently showed that peptides from several extracellular matrix (ECM) proteins,...
6.
Peptidoglycan in osteoarthritis synovial tissue is associated with joint inflammation
Holub M, Wahhab A, Rouse J, Danner R, McClune M, Dressler J, et al.
Res Sq . 2023 May; PMID: 37162851
Objectives: Peptidoglycan (PG) is an arthritogenic bacterial cell wall component whose role in human osteoarthritis is poorly understood. The purpose of this study was to determine if PG is present...