Joseph P Tinney
Overview
Explore the profile of Joseph P Tinney including associated specialties, affiliations and a list of published articles.
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27
Citations
567
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Recent Articles
1.
Keller B, Kowalski W, Tinney J, Tobita K, Hu N
J Cardiovasc Dev Dis
. 2020 Jun;
7(2).
PMID: 32545681
The goal of this review is to provide a broad overview of the biomechanical maturation and regulation of vertebrate cardiovascular (CV) morphogenesis and the evidence for mechanistic relationships between function...
2.
Dwenger M, Kowalski W, Ye F, Yuan F, Tinney J, Setozaki S, et al.
J Tissue Eng
. 2019 Apr;
10:2041731419841748.
PMID: 31024681
The immaturity of human induced pluripotent stem cell derived engineered cardiac tissues limits their ability to regenerate damaged myocardium and to serve as robust models for human disease and drug...
3.
Pandit H, Tinney J, Li Y, Cui G, Li S, Keller B, et al.
Ultrasound Med Biol
. 2018 Dec;
45(2):549-557.
PMID: 30527843
We developed a protocol to investigate and optimize the application of contrast-enhanced ultrasound (CEUS) to non-invasive diagnosis of progressing fatty liver disease in mouse models. Eighteen 4-wk-old male C57 L/J...
4.
Kowalski W, Yuan F, Nakane T, Masumoto H, Dwenger M, Ye F, et al.
Microsc Microanal
. 2017 Jun;
23(4):826-842.
PMID: 28625174
Biological tissues have complex, three-dimensional (3D) organizations of cells and matrix factors that provide the architecture necessary to meet morphogenic and functional demands. Disordered cell alignment is associated with congenital...
5.
Nakane T, Masumoto H, Tinney J, Yuan F, Kowalski W, Ye F, et al.
Sci Rep
. 2017 Apr;
7:45641.
PMID: 28368043
The current study describes a scalable, porous large-format engineered cardiac tissue (LF-ECT) composed of human induced pluripotent stem cells (hiPSCs) derived multiple lineage cardiac cells with varied 3D geometries and...
6.
Masumoto H, Nakane T, Tinney J, Yuan F, Ye F, Kowalski W, et al.
Sci Rep
. 2016 Jul;
6:29933.
PMID: 27435115
Human induced pluripotent stem cells (hiPSCs) are a robust source for cardiac regenerative therapy due to their potential to support autologous and allogeneic transplant paradigms. The in vitro generation of...
7.
Nguyen M, Tinney J, Ye F, Elnakib A, Yuan F, El-Baz A, et al.
Anal Chem
. 2014 Dec;
87(4):2107-13.
PMID: 25539164
Hemodynamic mechanical cues play a critical role in the early development and functional maturation of cardiomyocytes (CM). Therefore, tissue engineering approaches that incorporate immature CM into functional cardiac tissues capable...
8.
Kowalski W, Pekkan K, Tinney J, Keller B
Front Physiol
. 2014 Nov;
5:408.
PMID: 25374544
Innovative research on the interactions between biomechanical load and cardiovascular (CV) morphogenesis by multiple investigators over the past 3 decades, including the application of bioengineering approaches, has shown that the...
9.
Kowalski W, Teslovich N, Menon P, Tinney J, Keller B, Pekkan K
Dev Dyn
. 2014 May;
243(5):652-62.
PMID: 24868595
Background: Hypoplastic left heart syndrome (HLHS) is a major human congenital heart defect that results in single ventricle physiology and high mortality. Clinical data indicate that intracardiac blood flow patterns...
10.
Ye F, Yuan F, Li X, Cooper N, Tinney J, Keller B
Physiol Rep
. 2013 Dec;
1(5):e00078.
PMID: 24303162
Engineered cardiac tissues (ECTs) are platforms to investigate cardiomyocyte maturation and functional integration, the feasibility of generating tissues for cardiac repair, and as models for pharmacology and toxicology bioassays. ECTs...