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Hidetoshi Masumoto

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Articles 55
Citations 750
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Recent Articles
1.
Iida J, Kotani K, Murata K, Hakamada K, Maihemuti W, Mandai Y, et al.
Sci Rep . 2025 Feb; 15(1):4635. PMID: 39920228
This study explored the impact of hydrolyzed gelatin (HG) concentration on the retention and therapeutic efficacy of human iPS cell-derived cardiomyocytes (hiPSC-CMs) when injected into the myocardium. The solubility of...
2.
Maihemuti W, Murata K, Abulaiti M, Minatoya K, Masumoto H
Biochem Biophys Res Commun . 2024 Aug; 733:150605. PMID: 39197194
Electrical and dynamic stimulation are commonly employed to enhance the maturation of engineered cardiac tissue (ECT) derived from human induced pluripotent stem cells (iPSCs), reflecting the physiological environment of the...
3.
Yang Q, Murata K, Ikeda T, Minatoya K, Masumoto H
Sci Rep . 2024 Jun; 14(1):14811. PMID: 38926457
Ischemic heart diseases are a major global cause of death, and despite timely revascularization, heart failure due to ischemia-hypoxia reperfusion (IH/R) injury remains a concern. The study focused on the...
4.
Murata K, Makino A, Tomonaga K, Masumoto H
iScience . 2024 Feb; 27(1):108641. PMID: 38299028
Patients with chronic cardiomyopathy may have persistent viral infections in their hearts, particularly with SARS-CoV-2, which targets the ACE2 receptor highly expressed in human hearts. This raises concerns about a...
5.
Heima D, Takeda M, Tabata Y, Minatoya K, Yamashita J, Masumoto H
J Thorac Cardiovasc Surg . 2023 Nov; 168(3):e72-e88. PMID: 37981100
Objective: This study aimed to explore the therapeutic potential of human induced pluripotent stem cell (hiPSC)-derived cardiac tissues (HiCTs) in the emerging approach of bridge to recovery for severe heart...
6.
Kyo S, Murata K, Kawatou M, Minatoya K, Sunagawa G, Masumoto H
JTCVS Open . 2023 Jan; 12:201-210. PMID: 36590714
Objectives: Acute kidney injury is a serious complication after cardiovascular surgery requiring circulatory arrest. It is reported that mice can be induced into a hibernation-like hypometabolic state by stimulating a...
7.
Ho W, Kobayashi M, Murata K, Hashimoto Y, Izumi K, Kimura T, et al.
Sci Rep . 2022 Dec; 12(1):22294. PMID: 36566330
Decellularized xenogeneic vascular grafts can be used in revascularization surgeries. We have developed decellularization methods using high hydrostatic pressure (HHP), which preserves the extracellular structure. Here, we attempted ex vivo...
8.
Kanemitsu E, Zhao X, Iwaisako K, Inoue A, Takeuchi A, Yagi S, et al.
Transl Res . 2022 Nov; 255:26-36. PMID: 36347491
Cold storage is widely used to preserve an organ for transplantation; however, a long duration of cold storage negatively impacts graft function. Unfortunately, the mechanisms underlying cold exposure remain unclear....
9.
Osada H, Kawatou M, Fujita D, Tabata Y, Minatoya K, Yamashita J, et al.
JTCVS Open . 2022 Aug; 8:359-374. PMID: 36004071
Objectives: To establish a protocol to prepare and transplant clinical-grade human induced pluripotent stem cell (hiPSC)-derived cardiac tissues (HiCTs) and to evaluate the therapeutic potential in an animal myocardial infarction...
10.
Konegawa Y, Kuwahara T, Jo J, Murata K, Takeda T, Ikeda T, et al.
Eur J Cardiothorac Surg . 2022 Aug; 62(5). PMID: 35946548
Objectives: Excessive and chronic inflammation after a myocardial infarction (MI) is associated with left ventricular remodelling and impaired cardiac function. Among inflammatory cells, macrophages play a critical role in polarizing...