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Joseph P Flemming

Explore the profile of Joseph P Flemming including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 41
Followers 0
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Recent Articles
1.
Jackson Cullison S, Flemming J, Karagoz K, Wermuth P, Mahoney M
J Extracell Biol . 2024 Nov; 3(11):e70017. PMID: 39483807
The translation of pre-clinical anti-cancer therapies to regulatory approval has been promising, but slower than hoped. While innovative and effective treatments continue to achieve or seek approval, setbacks are often...
2.
Prajapati S, Flemming J, Khan D, Han H, How B, Rozenberg S, et al.
Immunotherapy . 2024 Aug; 16(14-15):925-935. PMID: 39119679
Atopic dermatitis (AD) often requires long-term treatment that may be associated with adverse effects. This review aims to characterize nemolizumab as a treatment for AD in adults. A literature search...
3.
Flemming J, Wermuth P, Mahoney M
J Invest Dermatol . 2023 Oct; 144(2):225-233. PMID: 37877931
The recent discovery of extracellular vesicles (EVs) carrying cargo consisting of various bioactive macromolecules that can modulate the phenotype of recipient target cells has revealed an important new mechanism through...
4.
Hill B, Calder A, Flemming J, Guo Y, Gilmore S, Trofa M, et al.
Mol Carcinog . 2023 Jul; 62(9):1428-1443. PMID: 37401875
Therapy using anti-PD-1 immune checkpoint inhibitors (ICI) has revolutionized the treatment of many cancers including head and neck squamous cell carcinomas (HNSCC), but only a fraction of patients respond. To...
5.
Flemming J, Hill B, Anderson-Pullinger L, Harshyne L, Mahoney M
JID Innov . 2021 Dec; 1(4):100053. PMID: 34909749
Exosomes or small extracellular vesicles (sEVs) are membrane-bound nanoparticles that carry various macromolecules and act as autocrine and paracrine signaling messengers. In this study, sEVs from epidermoid carcinoma cells influenced...
6.
Flemming J, Hill B, Haque M, Raad J, Bonder C, Harshyne L, et al.
J Extracell Vesicles . 2020 Sep; 9(1):1790159. PMID: 32944178
Abbreviations: Basal cell carcinomas, BCC; Betacellulin, BTC; 2-bromopalmitate, 2-Bromo; Cluster of differentiation, CD; Cytochrome c oxidase IV, COX IV; Desmoglein 2, Dsg2; Early endosome antigen 1, EEA1; Epidermal growth factor...