Adam J Luginbuhl
Overview
Explore the profile of Adam J Luginbuhl including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
249
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Recent Articles
1.
Mastrolonardo E, Llerena P, De Ravin E, Nunes K, Kaki P, Bridgham K, et al.
Cancer
. 2025 Mar;
131(6):e35799.
PMID: 40069917
Introduction/background: Obesity is a well-known risk factor for various cancers, yet emerging research demonstrates its association with improved survival outcomes in cancer treatment, labeled as "the obesity paradox." Studies investigating...
2.
Mastrolonardo E, Nunes K, Llerena P, Nikitina A, Sobol A, Scott E, et al.
Clin Cancer Res
. 2024 Nov;
31(3):515-528.
PMID: 39585339
Purpose: We evaluated whether indoleamine 2,3-dioxygenase (IDO1) inhibitor (IDOi) BMS986205 + PD-1 inhibitor nivolumab enhanced T-cell activity and augmented immune-mediated antitumor responses in untreated, resectable head and neck squamous cell...
3.
Nunes K, Jegede V, Mann D, Llerena P, Wu R, Estephan L, et al.
Laryngoscope
. 2024 Nov;
135(3):1090-1097.
PMID: 39530249
Objective: Application of virtual reality (VR) for surgical planning may improve clinical outcomes for head and neck cancer (HNC) resection. There is a lack of randomized trials and meaningful metrics...
4.
Bhattacharya P, Linnenbach A, South A, Martinez-Outschoorn U, Curry J, Johnson J, et al.
bioRxiv
. 2024 Oct;
PMID: 39386511
Immune checkpoint inhibition (ICI) has emerged as a critical treatment strategy for squamous cell carcinoma of the head and neck (HNSCC) that halts the immune escape of the tumor cells....
5.
Shing S, Armache M, Llerena P, OConnor M, Murphy K, Curry J, et al.
Ann Otol Rhinol Laryngol
. 2024 Oct;
133(12):1037-1041.
PMID: 39369307
Objectives: Tumors involving the vagus nerve are often clinically silent. We offer a case series with different clinical presentations and distinctive post-surgical sequelae that highlight some of the challenges associated...
6.
Mastrolonardo E, Llerena P, Lu J, Nunes K, Choi G, Amin D, et al.
JAMA Otolaryngol Head Neck Surg
. 2024 Jul;
150(8):688-694.
PMID: 38958948
Importance: For patients treated with immune checkpoint inhibitors (ICIs), recent data suggest that obesity has a beneficial effect on survival outcomes in various cancer types. Reports on this association in...
7.
Estephan L, Kumar G, Stewart M, Banoub R, Linnenbach A, Harshyne L, et al.
Front Oncol
. 2024 Jul;
14:1412212.
PMID: 38957320
Introduction: Oral cavity squamous cell carcinoma (OSCC) occurs most frequently in patients >60 years old with a history of tobacco and alcohol use. Epidemiological studies describe increased incidence of OSCC...
8.
Alnemri A, Tekumalla S, Moroco A, Vathiotis I, Tuluc M, Gargano S, et al.
Cancer Med
. 2024 Jun;
13(11):e7370.
PMID: 38847087
Objectives: Certain low-level immune-related adverse events (irAEs) have been associated with survival benefits in patients with various solid tumors on immune checkpoint inhibitors (ICIs). We aimed to investigate the association...
9.
Dyikanov D, Zaitsev A, Vasileva T, Wang I, Sokolov A, Bolshakov E, et al.
Cancer Cell
. 2024 May;
42(5):759-779.e12.
PMID: 38744245
The lack of comprehensive diagnostics and consensus analytical models for evaluating the status of a patient's immune system has hindered a wider adoption of immunoprofiling for treatment monitoring and response...
10.
Philips R, Alnemri A, Amin D, Patel J, Topf M, Johnson J, et al.
Cancer
. 2023 Oct;
130(6):863-875.
PMID: 37788128
Background: There is sparse literature on the effect of preoperative immunotherapy on complications after surgery for primary head and neck squamous cell carcinoma (HNSCC). The objectives are to compare complication...