David M Cognetti
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Explore the profile of David M Cognetti including associated specialties, affiliations and a list of published articles.
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79
Citations
788
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Recent Articles
1.
Mastrolonardo E, Llerena P, De Ravin E, Nunes K, Kaki P, Bridgham K, et al.
Cancer
. 2025 Mar;
131(6):e35799.
PMID: 40069917
Introduction/background: Obesity is a well-known risk factor for various cancers, yet emerging research demonstrates its association with improved survival outcomes in cancer treatment, labeled as "the obesity paradox." Studies investigating...
2.
Metkari A, Witt R, Cognetti D, Dhong C, Jia X
bioRxiv
. 2024 Dec;
PMID: 39651209
Towards the goal of engineering of functional salivary gland tissues, we cultured primary human salivary stem/progenitor cells (hS/PCs) in hyaluronic acid-based matrices with varying percentages of proteolytically degradable crosslinks in...
3.
Mastrolonardo E, Nunes K, Llerena P, Nikitina A, Sobol A, Scott E, et al.
Clin Cancer Res
. 2024 Nov;
31(3):515-528.
PMID: 39585339
Purpose: We evaluated whether indoleamine 2,3-dioxygenase (IDO1) inhibitor (IDOi) BMS986205 + PD-1 inhibitor nivolumab enhanced T-cell activity and augmented immune-mediated antitumor responses in untreated, resectable head and neck squamous cell...
4.
Nunes K, Jegede V, Mann D, Llerena P, Wu R, Estephan L, et al.
Laryngoscope
. 2024 Nov;
135(3):1090-1097.
PMID: 39530249
Objective: Application of virtual reality (VR) for surgical planning may improve clinical outcomes for head and neck cancer (HNC) resection. There is a lack of randomized trials and meaningful metrics...
5.
Goldberg Z, Jain A, Wu R, Cognetti D, Goldman R
Otolaryngol Head Neck Surg
. 2024 Aug;
172(1):91-99.
PMID: 39189141
Objective: Head and neck cancers (HNCs) have increased in prevalence and often require free-flap reconstruction (FFR) after tumor ablation. Postoperative complications following FFR can be high, occurring in as many...
6.
Mastrolonardo E, Llerena P, Lu J, Nunes K, Choi G, Amin D, et al.
JAMA Otolaryngol Head Neck Surg
. 2024 Jul;
150(8):688-694.
PMID: 38958948
Importance: For patients treated with immune checkpoint inhibitors (ICIs), recent data suggest that obesity has a beneficial effect on survival outcomes in various cancer types. Reports on this association in...
7.
Alnemri A, Tekumalla S, Moroco A, Vathiotis I, Tuluc M, Gargano S, et al.
Cancer Med
. 2024 Jun;
13(11):e7370.
PMID: 38847087
Objectives: Certain low-level immune-related adverse events (irAEs) have been associated with survival benefits in patients with various solid tumors on immune checkpoint inhibitors (ICIs). We aimed to investigate the association...
8.
Jain A, Goldberg Z, Briggs E, Amin D, Urdang Z, Goldman R, et al.
Laryngoscope
. 2024 Apr;
134(10):4278-4283.
PMID: 38651382
Objective: The modified frailty index (mFI-5) is a National Surgical Quality Improvement Program-derived 5-factor index that has been proven to reflect frailty and predict morbidity and mortality. We hypothesize that...
9.
Hoffman H, Koch M, Witt R, Ryan W, Zenk J, Katz P, et al.
Laryngoscope Investig Otolaryngol
. 2024 Feb;
9(1):e1224.
PMID: 38362174
Objectives: The Salivary Gland Committee of the American Academy of Otolaryngology-Head and Neck Surgery seeks to standardize terminology and technique for ultrasonograpy used in the evaluation and treatment of salivary...
10.
Sajisevi M, Nguyen K, Callas P, Holcomb A, Vural E, Davis K, et al.
JAMA Otolaryngol Head Neck Surg
. 2023 Dec;
150(2):107-116.
PMID: 38095911
Importance: Postoperative radiation therapy for close surgical margins in low- to intermediate-grade salivary carcinomas lacks multi-institutional supportive evidence. Objective: To evaluate the oncologic outcomes for low- and intermediate-grade salivary carcinomas...